Naturalproductman’s Blog

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Archive for the ‘Indoles’ Category

Penitrem biosynthesis

Posted by naturalproductman on April 12, 2015

Hideaki Oikawa and co-workers at Hokkaido University have reported in ACIE on the enzymatic biosynthesis of penitrem.

alkaloid

ACIE paper

Posted in Biosynthesis, Cyclobutanes, Diterpene, Enzymes, Indoles | Leave a Comment »

A few oxindoles

Posted by naturalproductman on January 18, 2015

Shuhua Qi and co-workers from CAS have reported in Tetrahedron on the isolation of cyclopiamides B-J.

oxindoles

Tetrahedron paper

Posted in Alkaloids, Indoles | Leave a Comment »

Looks like bromophakellin

Posted by naturalproductman on January 17, 2015

Michael Groll and co-workers at Michigan State have reported in ACIE on the target of of some indolo-phakellin natural products (proteasome).

phakellin

ACIE paper

Posted in Alkaloids, Chemical Biology, Indoles | Leave a Comment »

Alsmaphorazine D synthesis

Posted by naturalproductman on November 27, 2014

Hanfeng Ding and co-workers have reported in ACIE on the synthesis of alsmaphorazine D.
indole

ACIE paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

Hapalindole alkaoid syntheses

Posted by naturalproductman on October 11, 2014

Ang Li and co-workers from SIOC have reported in ACIE on the syntheses of hapalindole compounds.

hapalindole

ACIE paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

Unified strategies are in

Posted by naturalproductman on October 7, 2014

Jieping Zhu and co-workers from CNRS have reported in JACS on the syntheses of some alkaloids, goniomitine, 1,2-dehydroaspidospermidine, aspidospermidine, vincadifformine, and kopsihainanine A.

 

JACS paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

Indole alkaloid synthesis

Posted by naturalproductman on July 15, 2014

Corey Stephenson and colleague at the University of Michigan have reported in JACS on the synthesis of pseudotabersonine. A mental roadblock for me was when I was looking at the paper, I was trying to find the structure of catalyst 5, which was the iridium catalyst used for a ring opening reaction, but just found the number 5 in the scheme. Within the text of the paper however it says Ir(dF(CF3)ppy)2(dtbbpy)PF6, which was cited with a Sigma Aldrich catalog number.

 

photoredox

JACS paper

Posted in Alkaloids, Indoles, Iridium, Light Mediated, Methodology, Transition Metal | Leave a Comment »

Dimerization, electrochemically

Posted by naturalproductman on April 18, 2014

Phil Baran and co-workers reported in JACS on a synthesis of dixiamycin via electrochemical dimerization. I usually think of Kevin Moeller from Washington University in St. Louis when I see electrochemical reactions.

JACS paper

Posted in Dimer, Electrochemical, Indoles, Methodology, Total Synthesis | Leave a Comment »

Indole alkaloids

Posted by naturalproductman on December 17, 2013

Jieping Zhu and co-workers haver reported in JACS on the syntheses of some indole alkaloids.

indole

 

 

JACS paper

Posted in Alkaloids, Indoles, Methodology, Total Synthesis | Leave a Comment »

Chimonanthine synthesis

Posted by naturalproductman on October 11, 2013

Dawei Ma and co-workers at SIOC have reported in ACIE on the synthesis of

indole

ACIE paper

Posted in Indoles, Total Synthesis | Leave a Comment »

 
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