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Archive for the ‘Methodology’ Category

Chlorinated vinyl epoxide ring opening with TMS chloride

Posted by naturalproductman on March 29, 2015

Erick Carreira and co-workers have reported in Organic Letters on a chlorinated vinyl epoxide ring opening using TMS chloride.
TMSCl
OL paper

Posted in Cascade Reactions, Methodology | Leave a Comment »

Substituted benzaldehydes via NHCs

Posted by naturalproductman on March 25, 2015

David Lupton and co-workers at Monash University have reported in Chemical Science on a method to synthesize substituted benzenes from acyclic precursors.
benzene
Chemical Science paper

Posted in Carbene, Cascade Reactions, Methodology | Leave a Comment »

[2+2] via oxazaborolidine

Posted by naturalproductman on March 22, 2015

M. Kevin Brown and co-workers at Indiana University have reported in JACS on an asymmetric [2+2] using an oxazaborolidine catalyst.

2+2

JACS paper

Posted in Asymmetric, Cycloaddition, Methodology, [2+2] | Leave a Comment »

C-H activation with Pd

Posted by naturalproductman on March 21, 2015

Erik Alexanian and co-workers have reported in JACS on a palladium catalyzed C-H arylation from alkyl halides.
palladium
JACS paper

Posted in C-H activation, Methodology, Palladium, Transition Metal | 1 Comment »

Bromochlorination of allylic alcohols

Posted by naturalproductman on March 21, 2015

Noah Burns and co-workers at Stanford have reported in JACS on a bromo-chlorination of allylic alcohols.
bromochlorination

JACS paper

Posted in Methodology, Titanium, Transition Metal | Leave a Comment »

Leucosceptroids synthesis

Posted by naturalproductman on March 21, 2015

Thomas Magauer and colleague at Ludwig-Maximilians-University Munich have reported in JACS on the synthesis of leucosceptroids.

leucosceptroid

JACS paper

Posted in Methodology, Total Synthesis | Tagged: | Leave a Comment »

Synthesis of Leupyrrin A1

Posted by naturalproductman on March 21, 2015

Dirk Mensche and co-workers at Universität Bonn have reported in JACS on the synthesis of

synthesis

JACS paper

Posted in Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Diazonamide analogs through electrochemistry

Posted by naturalproductman on March 5, 2015

Patrick Harran and co-workers have reported in ACIE on an electrochemical approach to access diazonamide analogs.
diazonamide
ACIE paper

Posted in Electrochemical, Macrocycles, Methodology, Oxazoles, Total Synthesis | Leave a Comment »

Silver mediated (stoichiometric) C-H activation

Posted by naturalproductman on March 5, 2015

Pingping Tang and co-workers from Nankai University have reported in ACIE on a silver mediated trifluoromethylthiolation.

silver

ACIE paper

Posted in C-H activation, Methodology, Silver, Transition Metal | Leave a Comment »

Rh-catalyzed cascade

Posted by naturalproductman on March 5, 2015

P. Andrew Evans and co-workers at Queen’s University have reported in ACIE on a rhodium catalyzed [(3+2)+2] carbocyclization.

rhodium

ACIE paper

Posted in Cascade Reactions, Methodology, Rhodium, Transition Metal | Leave a Comment »

 
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