Naturalproductman’s Blog

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Archive for the ‘Methodology’ Category

Diazonamide analogs through electrochemistry

Posted by naturalproductman on March 5, 2015

Patrick Harran and co-workers have reported in ACIE on an electrochemical approach to access diazonamide analogs.
diazonamide
ACIE paper

Posted in Electrochemical, Macrocycles, Methodology, Oxazoles, Total Synthesis | Leave a Comment »

Silver mediated (stoichiometric) C-H activation

Posted by naturalproductman on March 5, 2015

Pingping Tang and co-workers from Nankai University have reported in ACIE on a silver mediated trifluoromethylthiolation.

silver

ACIE paper

Posted in C-H activation, Methodology, Silver, Transition Metal | Leave a Comment »

Rh-catalyzed cascade

Posted by naturalproductman on March 5, 2015

P. Andrew Evans and co-workers at Queen’s University have reported in ACIE on a rhodium catalyzed [(3+2)+2] carbocyclization.

rhodium

ACIE paper

Posted in Cascade Reactions, Methodology, Rhodium, Transition Metal | Leave a Comment »

Efavirenz flow synthesis

Posted by naturalproductman on March 5, 2015

Peter Seeberger and co-workers at Max Planck Institute of Colloids and Interfaces have reported in ACIE on the flow synthesis of efavirenz.

flow

ACIE paper

Posted in Flow, HIV, New Setups, Total Synthesis | Leave a Comment »

Cycloclavine biosynthesis

Posted by naturalproductman on March 5, 2015

Sarah O’Connor and co-workers from the John Innes Centre in the UK have reported in ACIE on the biosynthesis of cycloclavine.

cycloclavine

ACIE paper

Posted in Alkaloids, Biosynthesis, Enzymatic, Enzymes, Methodology | Leave a Comment »

Dictyodendrin B via C-H activations

Posted by naturalproductman on March 5, 2015

Matthew Gaunt and co-workers at the University of Cambridge have reported in ACIE on the synthesis of dictyodendrin B.
C-H

ACIE paper

Posted in Alkaloids, C-H activation, Methodology, Total Synthesis | Leave a Comment »

Epoxide and aryl halide coupling

Posted by naturalproductman on March 5, 2015

Daniel Weix and colleague at the University of Rochester have reported in JACS on a coupling between an epoxide and an aryl halide.

epoxide

JACS paper

Posted in Methodology, Nickel, Titanium, Transition Metal | Leave a Comment »

1,1-Arylborylation of terminal alkenes

Posted by naturalproductman on March 5, 2015

Dean Toste and co-workers have reported in JACS on a 1,1-arylborylation of terminal alkenes.

arylborylation

JACS paper

Posted in Cascade Reactions, Methodology, Palladium, Transition Metal | Leave a Comment »

B-H insertions

Posted by naturalproductman on March 5, 2015

Ming-Hua Xu and co-workers from the Chinese Academy of Sciences have reported in JACS on a rhodium catalyzed transformation of a diazo to an organoborane.

B-H

JACS paper

Posted in Carbene, Cascade Reactions, Methodology, Rhodium, Transition Metal | Leave a Comment »

Gold cascade

Posted by naturalproductman on March 5, 2015

Dean Toste and co-workers have reported in JACS on a gold catalyzed Rautenstrauch cascade reaction.

gold

JACS paper

Posted in Cascade Reactions, Gold, Methodology, Named Reactions, Rautenstrauch rearrangement, Transition Metal | Leave a Comment »

 
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