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Archive for the ‘Carbene’ Category

Sulfur ylides with copper allenylidenes

Posted by naturalproductman on July 4, 2016

Wen-Jing Xiao and co-workers from Central China Normal University have reported in JACS on an asymmetric [4+1] reaction between a copper allenylidene and sulfur ylide.

 

JACS paper

Posted in Asymmetric, Carbene, Copper, Methodology, Transition Metal | Leave a Comment »

Palladium Carbenes

Posted by naturalproductman on April 19, 2016

Daniel Sole and co-workers at Universidad Complutense de Madrid have reported in ACIE on the generation of palladium carbenoids from diazo precursors to effect an intramolecular C-H insertion.

 

ACIE paper

Posted in Carbene, Methodology, Palladium | Leave a Comment »

Ni-catalyzed cyclopropanation

Posted by naturalproductman on July 30, 2015

Peter Chen and co-workers from ETH Zurich have reported in ACIE on a nickel catalyzed cyclopropanation. Looks similar to a Corey-Chaykovsky cyclopropanation because of the formation of an ylide.

nickel

ACIE paper

Posted in Carbene, Cascade Reactions, Methodology, Nickel, Transition Metal | Leave a Comment »

From carbenoids to allenoates

Posted by naturalproductman on July 1, 2015

Xiaoming Feng and co-workers from Sichuan University have reported in the transformation of terminal alkynes to allenoates using diazo acetates.

diazo

ACIE paper

Posted in Carbene, Methodology, Organocatalytic | Leave a Comment »

B-H Functionalization

Posted by naturalproductman on April 12, 2015

Ming-Hua Xu and co-workers from the Chinese Academy of Sciences have reported in JACS on a rhodium catalyzed carbene insertion into a B-H bond.

B-H

JACS paper

Posted in Carbene, Methodology, Rhodium, Transition Metal | Leave a Comment »

Substituted benzaldehydes via NHCs

Posted by naturalproductman on March 25, 2015

David Lupton and co-workers at Monash University have reported in Chemical Science on a method to synthesize substituted benzenes from acyclic precursors.
benzene
Chemical Science paper

Posted in Carbene, Cascade Reactions, Methodology | Leave a Comment »

B-H insertions

Posted by naturalproductman on March 5, 2015

Ming-Hua Xu and co-workers from the Chinese Academy of Sciences have reported in JACS on a rhodium catalyzed transformation of a diazo to an organoborane.

B-H

JACS paper

Posted in Carbene, Cascade Reactions, Methodology, Rhodium, Transition Metal | Leave a Comment »

NHC-catalyzed [4+2]

Posted by naturalproductman on October 4, 2014

David Lupton and co-worker at Monash University have reported in JACS on an NHC-catalyzed [4+2] reaction.
4+2

JACS paper

Posted in Carbene, Cascade Reactions, Methodology | Leave a Comment »

Dihydropyran access

Posted by naturalproductman on May 6, 2014

Carlos Saa and co-workers at Universidad de Santiago de Compostela have reported in ACIE on a reaction involving a ruthenium cascade followed by C-O formation to form dihydropyrans.

ruthenium
ACIE paper

Posted in Carbene, Cascade Reactions, Methodology, Ruthenium, Transition Metal | Leave a Comment »

Pyridines from 2H-azirines

Posted by naturalproductman on January 16, 2013

Cheol-Min Park and co-workers from Nanyang Technological University in Singapore have reported in ACIE on the synthesis of pyridines from 2H-azirines.

carbene

ACIE paper

Posted in Carbene, Cascade Reactions, Methodology, Rhodium, Transition Metal | Leave a Comment »

 
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