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Archive for the ‘cross coupling’ Category

Metal Catalyzed Cross Coupling Reactions

Methyl ether + Grignard

Posted by naturalproductman on May 29, 2016

Naoto Chatani and co-workers from Osaka University have reported in JACS on a methyl ether coupling reaction with a Grignard reagent.

 

JACS paper

Posted in cross coupling, Methodology, Nickel, Transition Metal | Leave a Comment »

Iron-catalyzed cross coupling between Grignard reagents and enol carbamates

Posted by naturalproductman on May 3, 2016

Doug Frantz and co-workers from UTSA have reported in ACIE on an iron-catalyzed cross-coupling reaction between enol carbamates and Grignard reagents.

 

ACIE paper

Posted in cross coupling, Iron, Methodology, Transition Metal | Leave a Comment »

Desymmetrization with proline and Pd

Posted by naturalproductman on April 19, 2016

Yi-Xia Jia and co-workers from Zhejiang University have reported in JACS on an intramolecular desymmetrization by a Heck reaction.

 

JACS paper

Posted in Desymmetrization, Heck, Methodology, Mizoroki-Heck, Organocatalytic, Palladium, Transition Metal | Leave a Comment »

Asymmetric copper catalyzed C-N coupling

Posted by naturalproductman on February 12, 2016

Greg Fu and Jonas Peters and co-workers at Caltech have reported in Science on a copper catalyzed asymmetric C-N bond coupling reaction that required blue light.

 

Science paper

Posted in Asymmetric, Copper, cross coupling, Methodology | Leave a Comment »

Rest in Peace Richard Heck

Posted by naturalproductman on December 9, 2015

ACIE paper

Posted in cross coupling, Heck, Random | Leave a Comment »

Pd-cross coupling with vinylogous enolates

Posted by naturalproductman on October 28, 2015

Troels Skrydstrup and co-workers at Aarhus University have reported in JACS on a palladium catalyzed coupling between Csp2-iodides and vinylogous enolates.
enolate

JACS paper

Posted in cross coupling, Methodology, Palladium, Transition Metal | Leave a Comment »

Leustroducsin B synthesis

Posted by naturalproductman on September 2, 2015

Barry Trost and co-workers have reported in JACS on the synthesis of leustroducsin B (39 steps).

leustroducsin B

JACS paper

Posted in cross coupling, Methodology, Total Synthesis | Leave a Comment »

Photoredox cross-coupling

Posted by naturalproductman on August 31, 2015

Larry Overman and co-workers reported in JACS on a photoredox coupling between tertiary alcohols and electron deficient olefins.

JACS paper

Posted in cross coupling, Light Mediated, Methodology | Leave a Comment »

Aryl bromide and aryl triflate cross coupling with Ni and Pd

Posted by naturalproductman on August 28, 2015

Daniel Weix and co-workers have reported in Nature on a multimetallic cross coupling between an aryl triflate and aryl bromide using palladium and nickel.

Nature paper

Posted in Cooperative Catalysis, cross coupling, Methodology, Nickel, Palladium, Transition Metal | Leave a Comment »

Iron cross coupling with vinyl acetates

Posted by naturalproductman on July 17, 2015

Axel Jacobi von Wangelin and co-workers at the University of Regensburg have reported in ACIE on an iron catalyzed cross coupling between alkenyl acetates and an alkyl magnesium halide unit.

iron

ACIE paper

Posted in cross coupling, Iron, Transition Metal | Leave a Comment »