David Nagib and co-workers from the Ohio State University have reported in ACIE on a triiodide mediated C-H amination reaction.
Posted by naturalproductman on July 31, 2016
David Nagib and co-workers from the Ohio State University have reported in ACIE on a triiodide mediated C-H amination reaction.
Posted in C-H activation, Hypervalent Iodine, Methodology | Leave a Comment »
Posted by naturalproductman on April 7, 2016
Ryan Gilmour and colleague at Westfal̈ische Wilhelms-Universitaẗ Münster have reported in JACS on a difluorination of an olefin using p-iodotoluene, selectfluor, and various sources of amine-HF including TREAT-HF (triethylamine trihydrofluoride). They also try to expand on the transformation by making it asymmetric using a C2-symmetric chiral aryl iodide.
Posted in Hypervalent Iodine, Methodology | Leave a Comment »
Posted by naturalproductman on April 5, 2016
Eric Jacobsen and co-workers reported in JACS on a difluorination of an olefin. They accomplished this transformation by using mCPBA (1.1 equivalent), HF-pyridine (100 equivalents of HF), and an aryl iodide derivative (catalyst).
Posted in Hypervalent Iodine, Mechanistic, Methodology | Leave a Comment »
Posted by naturalproductman on February 24, 2016
Takashi Ohshima and co-workers from Kyushu University reported in JACS on the use of hypervalent iodine to perform an N-H insertion
Posted in C-H activation, Hypervalent Iodine, Methodology, Nitrene | Leave a Comment »
Posted by naturalproductman on January 28, 2016
Srinivasan Chandrasekaran and colleague at the Indian Institute of Science have reported in Tetrahedron on a mechanistically interesting transformation involving a geminal aminooxygenation of a vinyl arene. Two different reaction conditions were identified: one with m-CPBA, the other with a hypervalent iodine reagent. The former underwent a deuterium shift on the gem-dideuterated-styrene starting material and the latter does not.
Posted in Cascade Reactions, Hypervalent Iodine, Mechanistic, Methodology | Leave a Comment »
Posted by naturalproductman on November 24, 2015
Hao Xu’s lab in University of Georgia have reported on an iron-catalyzed diazidation of olefins.
Dorian Didier’s lab from LMU Munich reported on an interesting one-pot reaction.
Posted in Cascade Reactions, Hypervalent Iodine, Methodology, Structural Reassignment, Total Synthesis | Leave a Comment »
Posted by naturalproductman on October 1, 2015
Xin-Hua Duan and co-workers from Xi’an Jiaotong University have reported in Organic Letters on a hypervalent iodine approach to accessing alkynylated ketones.
Posted in Cascade Reactions, Hypervalent Iodine, Methodology | Leave a Comment »
Posted by naturalproductman on May 2, 2015
Antonio Herrera and co-workers from CSIC have reported in Organic Letters on a hypervalent iodine approach to access lactams from linear precursors.
Posted in Hofmann–Löffler–Freytag-type, Hypervalent Iodine, Methodology, Named Reactions | Leave a Comment »
Posted by naturalproductman on April 12, 2015
Mikiko Sodeoka and co-workers from RIKEN have reported in JACS on a aminotrifluoromethylation of olefins using a hypervalent iodine reagent.
Posted in Hypervalent Iodine, Methodology | Leave a Comment »