Naturalproductman’s Blog

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Archive for the ‘Nitrene’ Category

α-Aminations via Nitrenoids

Posted by naturalproductman on February 24, 2016

Takashi Ohshima and co-workers from Kyushu University reported in JACS on the use of hypervalent iodine to perform an N-H insertion



JACS paper

Posted in C-H activation, Hypervalent Iodine, Methodology, Nitrene | Leave a Comment »

Sialic acid synthesis

Posted by naturalproductman on November 3, 2011

Xue-Wei Liu and co-workers from Nanyang Technological University in Singapore have reported in ACIEE on the synthesis of sialic acid starting from a dihydropyran.


ACIEE paper

Posted in Asymmetric, Cascade Reactions, Glycosides, Methodology, Nitrene, Rhodium, Transition Metal | Leave a Comment »

N-chlorocarbamate = nitrene

Posted by naturalproductman on October 14, 2011

Carl Lovely and colleague at UT Arlington have reported in Organic Letters on the use of an N-chlorocarbamate reagent that is basically the equivalent of a nitrene.  Interestingly they use an imidazolinium substrate – that we usually see in the benzoin condensations – and reacts with the N-chlorocarbamate reagent to form the new C-N double bond.


OL paper

Posted in Cascade Reactions, Methodology, Nitrene | Leave a Comment »