Yandong Zhang and co-workers at Xiamen University have reported in Organic Letters on a synthesis of fusarisetin A using a one pot intramolecular Diels-Alder/Mukaiyama aldol reaction cascade sequence.
Archive for the ‘One pot’ Category
Posted by naturalproductman on January 27, 2016
Posted by naturalproductman on November 21, 2012
Looking at this molecule, one would never think that you can mix three things, a penta-substituted benzene ring, benzaldehyde and humulene, and obtain the final compound, guajadial! Ji-Kai Liu and co-workers at the Kunming Institute of Botany did such a thing!
Posted by naturalproductman on April 25, 2012
Zhigang Weng and co-workers from Shenzhen University have reported in Tetrahedron on a synthesis of angelone. The highlight is the cascade reaction forming the final product.
Posted by naturalproductman on October 19, 2011
Istvan Marko and co-workers at Université catholique de Louvain in Belgium have reported in Tetrahedron on a nice synthesis of Telaprevir using an oxaziridine and a lithium amide to functionalize an alkene.