Guangbin Dong and colleague have reported in JACS on an intramolecular coupling between cyclobutanones and allenes.
Archive for the ‘Ring forming’ Category
This reaction involves different ways to form rings from acyclic precursors.
Chlorinated tetrahydropyran opening
Posted by naturalproductman on August 5, 2015
Elizabeth Jarvo and co-workers at UC Irvine have reported in JACS on a cyclopropane ring formation from a chlorinated tetrahydropyran.
Posted in Cascade Reactions, Methodology, Ring forming | Leave a Comment »
Sn2 prime with trichloroacetimidates
Posted by naturalproductman on May 28, 2015
At first look of the abstract figure I thought this was an Overman rearrangement paper but no, trichloroacetimidates are also good leaving groups for Sn2 prime reactions.
Posted in Cascade Reactions, Methodology, Ring forming, Sn2 prime | Leave a Comment »
Salvileucalin C synthesis
Posted by naturalproductman on June 6, 2014
Hanfeng Ding and co-workers from Zhejiang University have reported in Organic Letters on the synthesis of salvileucalin C. I thought of Sarah Reisman’s work but she of course made salvileucalin B. By the way, I noticed that Sarah Reisman was promoted directly from assistant prof to prof at Caltech so kudos to her.
Posted in Methodology, Ring forming, Total Synthesis, Transannular | Leave a Comment »
Andrastin C synthesis
Posted by naturalproductman on November 19, 2012
Masahiro Toyota and co-workers from Tohoku University have reported in JOC on the synthesis of andrastin C.
Posted in Cascade Reactions, Methodology, Ring forming, Steroids | Leave a Comment »
Cyclization through fluorination
Posted by naturalproductman on October 25, 2012
Guosheng Liu and colleague at the Chinese Academy of Science have reported in Org Lett on a fluorination reaction that involves ring formation.
Posted in Cascade Reactions, Methodology, Ring forming | Leave a Comment »