Naturalproductman’s Blog

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Archive for the ‘Cobalt’ Category

Naseseazines synthesis

Posted by naturalproductman on September 4, 2011

Mohammed Movassaghi and co-worker have reported in JACS on their synthesis of naseseazines.

naseseazines

JACS paper

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Posted in Alkaloids, Asymmetric, Cobalt, Dimer, Indoles, Methodology, Total Synthesis, Transition Metal | Leave a Comment »

Cobalt catalyzed Michael addition of alkyne to enone

Posted by naturalproductman on August 18, 2011

Tamio Hayashi and co-workers at Kyoto University have reported in Chem Comm on a cobalt catalyzed Michael addition of an alkyne onto an enone.

cobalt

Chem Comm paper

Posted in Asymmetric, Cobalt, Methodology, Michael, Named Reactions, Transition Metal, Zinc | Leave a Comment »

Lactone formation

Posted by naturalproductman on August 16, 2011

Akiya Ogawa and co-workers at Osaka University have reported in Organometallics on a cobalt catalyzed reaction that forms lactones from an alkyne and two CO units.

cobalt

OM paper

Posted in Cascade Reactions, Cobalt, Methodology, Multi-Component Coupling, Transition Metal | Leave a Comment »

Scalable syntheses of axinellamines

Posted by naturalproductman on August 16, 2011

Phil Baran and co-workers have reported in JACS on their scalable synthesis of axinellamines.

axinellamines

JACS paper

Posted in Alkaloids, Barbier, Cascade Reactions, Cobalt, Methodology, Named Reactions, Pauson-Khand, Transition Metal | Leave a Comment »

Cobalt Catalyzed Conjugate Addition

Posted by naturalproductman on April 18, 2011

Chien-Hong Cheng and co-workers at the National Tsing Hua University in Taiwan have published in JACS on a cobalt catalyzed alkyne addition onto an enone.

Michael

JACS paper

Posted in Cobalt, Conjugate Additions, Methodology, Transition Metal | Leave a Comment »

Meloscine Synthesis

Posted by naturalproductman on March 8, 2011

Chisato Mukai and colleagues have reported in Organic Letters on their synthesis of meloscine via a Pauson-Khand reaction.

meloscine

 

OL paper

Posted in Alkaloids, Cascade Reactions, Cobalt, Methodology, Named Reactions, Pauson-Khand, Ring forming, Transition Metal | Leave a Comment »

Oxidation/Cyclization Cascade

Posted by naturalproductman on February 24, 2011

Jens Hartung and co-workers at Technische Universitat Kaiserslautern have reported in JACS on a cobalt catalyzed formation of a substituted tetrahydrofuran product from an alkenol and an alkynoate.

cobalt

JACS paper

Posted in Cascade Reactions, Cobalt, Methodology, Transition Metal | Leave a Comment »

Asymmetric Cyclopropenation

Posted by naturalproductman on February 20, 2011

Peter Zhang and co-workers from the University of South Florida have published in JACS on a cyclopropenation reaction starting with diazo compounds and alkynes.

cyclopropenation

 

JACS paper

Posted in Carbene, Cascade Reactions, Cobalt, Methodology, Transition Metal | Leave a Comment »

[6+2] with Cobalt

Posted by naturalproductman on December 16, 2010

Gerard Buono and co-workers at CNRS have published in Organic Letters on a Cobalt mediated [6+2] cycloaddition.

6+2

 

OL paper

Posted in Allenes, Cascade Reactions, Cobalt, Cycloaddition, Methodology, Transition Metal | Leave a Comment »

[4+2] with Cobalt-Alkynes

Posted by naturalproductman on September 6, 2010

Jun Takaya and co-workers at Tokyo Institute of Technology have published a masked cyclic alkyne using cobalt.  These cobalt-alkyne complexes readily undergo [4+2] cycloadditions.

cobalt alkyne

ACIEE paper

Posted in Cascade Reactions, Cobalt, Cycloaddition, Methodology, Pericyclic reactions, Transition Metal | Leave a Comment »