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Archive for the ‘Copper’ Category

Sulfur ylides with copper allenylidenes

Posted by naturalproductman on July 4, 2016

Wen-Jing Xiao and co-workers from Central China Normal University have reported in JACS on an asymmetric [4+1] reaction between a copper allenylidene and sulfur ylide.

 

JACS paper

Posted in Asymmetric, Carbene, Copper, Methodology, Transition Metal | Leave a Comment »

Cu-catalyzed [1+1+1]

Posted by naturalproductman on April 5, 2016

Andrey Antonchick and colleague at Technische Universität Dortmund have reported in ACIE on a copper catalyzed [1+1+1] reaction to form cyclopropanes.

 

ACIE paper

Posted in Copper, Methodology | Leave a Comment »

Asymmetric copper catalyzed C-N coupling

Posted by naturalproductman on February 12, 2016

Greg Fu and Jonas Peters and co-workers at Caltech have reported in Science on a copper catalyzed asymmetric C-N bond coupling reaction that required blue light.

 

Science paper

Posted in Asymmetric, Copper, cross coupling, Methodology | Leave a Comment »

Diacyl peroxide + Olefin = Alkyl-ester + CO2

Posted by naturalproductman on January 21, 2016

Hongli Bao and co-workers from the Chinese Academy of Sciences have reported in Organic Letters on a copper catalyzed reaction that adds an ester group and an R group across an olefin using a diacyl peroxide. To make these daily peroxides (which are potentially explosive), they treated acyl chlorides with hydrogen peroxide.

 

OL paper

Posted in Cascade Reactions, Copper, Transition Metal | Leave a Comment »

Sigmatropic rearrangement cascade

Posted by naturalproductman on October 28, 2015

Here’s another example of the student who published a single author paper. Yang Yang at MIT from Buchwald’s lab reported in ACIE on a very cool sigmatropic rearrangement.
sigmatropic
ACIE paper

Posted in Cascade Reactions, Copper, Sigmatropic Rearrangements, Transition Metal | Leave a Comment »

Steroid C12-hydroxylation published in JACS

Posted by naturalproductman on October 22, 2015

Phil Baran and co-workers reported in JACS on a copper catalyzed C12-hydroxylation reaction.
C12
 

 

JACS paper

Posted in C-H activation, Copper, Methodology, Steroids, Transition Metal | Leave a Comment »

C-H oxidation

Posted by naturalproductman on October 7, 2015

Melanie Sanford and colleague have reported in JACS on a Pt-catalyzed terminal C-H oxidation of aliphatic amines.

C-H

JACS paper

Posted in C-H activation, Copper, Methodology, Platinum, Transition Metal | Leave a Comment »

Asymmetric copper catalyzed Michael Addition

Posted by naturalproductman on August 19, 2015

Jean-Marc Campagne and co-workers at CNRS have reported in ACIE on a copper catalyzed asymmetric Michael addition.
copper

ACIE paper

Posted in Asymmetric, Copper, Methodology, Transition Metal | Leave a Comment »

Guanacastepene syntheses

Posted by naturalproductman on July 11, 2015

Chin-Kang Sha and colleague from National Tsing-Hua University have reported in Organic Letters on the syntheses of guanacastapenes N and O.

guanacastepene

OL paper

Posted in Copper, Diels-Alder, Kinetic resolution, Methodology, Named Reactions, Radical Chemistry, Sesquiterpenes, Total Synthesis, Transition Metal | Leave a Comment »

Syn-1,3-carbonate access

Posted by naturalproductman on May 28, 2015

Matthew Gaunt and colleague at the University of Cambridge have reported in ACIE on a method for the synthesis of syn-1,3-carbonates.

Cu

ACIE paper

Posted in Copper, Hypervalent Iodine, Methodology, Transition Metal | Leave a Comment »

 
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