Posted by naturalproductman on November 4, 2011
Amir Hoveyda and co-workers from Boston College have reported in Nature on a ring closing metathesis approach to access macrocyclic natural products with a Z-olefin using a tungsten alkylidene.
Posted in Metathesis, Methodology, Ring forming, Total Synthesis, Transition Metal, Tungsten | Leave a Comment »
Posted by naturalproductman on June 5, 2011
Sakae Aoyagi and colleague at the Tokyo Pharmaceutical University have reported in Chem Comm on the synthesis of chamobtusin, a diterpenoid alkaloid. A tungsten mediated oxidation protocol was used to access the pyrrole from a tetrahydropyrrole.
Chem Comm paper
Posted in Alkaloids, Cascade Reactions, Diterpenoids, Methodology, Michael, Named Reactions, Ring forming, Transition Metal, Tungsten | Leave a Comment »
Posted by naturalproductman on February 24, 2011
Panahi and colleague from Shiraz University in Iran have reported in Synthesis on a four component coupling reaction to form dihydropyrimido[4,5-b]quinolinetrione derivatives.
Posted in Cascade Reactions, Methodology, Transition Metal, Tungsten | Leave a Comment »
Posted by naturalproductman on February 1, 2010
Gerard Parkin and co-worker at Columbia University have recently published in Nature on a tungsten complex that breaks C-C bonds of aromatic rings.
Posted in C-C Bond Breaking, Methodology, Transition Metal, Tungsten | Leave a Comment »