Subhas Bose and co-worker at the Indian Institute of Chemical Technology have recently published in Chemical Communications on the synthesis of circumdatin H, an NADH oxidase inhibitor. The key reaction was an Eguchi-aza-Wittig reaction to form the carbon nitrogen double bond.
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Circumdatin H Synthesis
Posted by naturalproductman on January 9, 2010
Posted in Alkaloids, Eguchi aza-Wittig, Methodology, Ring forming, Staudinger | Leave a Comment »