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Circumdatin H Synthesis

Posted by naturalproductman on January 9, 2010

Subhas Bose and co-worker at the Indian Institute of Chemical Technology have recently published in Chemical Communications on the synthesis of circumdatin H, an NADH oxidase inhibitor.  The key reaction was an Eguchi-aza-Wittig reaction to form the carbon nitrogen double bond.

circumdatin H
Synthesis paper

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