Some [2+2] cycloaddition chemistry

Tehshik Yoon and co-workers published in Organic Letters on a [2+2] photocycloaddition.

OL paper

Nessan Kerrigan and co-workers at Oakland University have reported in JACS on a [2+2] reaction between ketenes to form beta-lactones.

JACS paper

At first look at Daniel Romo’s name I thought of Tony Romo and funny enough they’re both in Texas.  Here they report on a Mukaiyama Aldol lactonization to form beta-lactones.

JACS paper

Michael addition

Michael Doyle and colleagues in Maryland have reported on a asymmetric Michael addition.  They used an HFIP (hexafluoroisopropanol) additive and bis-oxazoline ligand.

ACIEE paper

Formal Synthesis of GB13 and Synthesis of GB16

Some molecules will always be a challenging target no matter how much chemical technology advances.  Dawei Ma and co-workers at Shanghai Institute of Organic Chemistry have published in ACIEE on the synthesis of galbulimima alkaloid GB16 and in the addition to a formal synthesis of GB13.

ACIEE paper

Aldols with Diazocompounds

Michael Doyle and co-worker at the University of Maryland have successfully done an Aldol reaction on diazocompounds using the Mukaiyama Aldol protocol.

OL paper