Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for the ‘retro-Mannich’ Category

Phalarine Synthesis

Posted by naturalproductman on May 28, 2010

Samuel Danishefsky and co-workers have published in JACS on the total synthesis of phalarine from an amino acid.


JACS paper

Posted in Alkaloids, Cascade Reactions, Methodology, Named Reactions, Pictet-Spengler, retro-Mannich | Leave a Comment »


Posted by naturalproductman on April 30, 2010

James White and co-workers have recently reported in JOC on a [2+2] photocycloaddition followed by a retro-Mannich cascade reaction (TIPCARM), which further undergoes another retro-Mannich reaction and a rearrangement to yield a spirocycle.


JOC paper

Posted in Cascade Reactions, Cycloaddition, Light Mediated, Methodology, Named Reactions, Pericyclic reactions, retro-Mannich | Leave a Comment »