Naturalproductman’s Blog

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Archive for the ‘New Types’ Category

TTN Ring Contraction

Posted by naturalproductman on February 27, 2009

The ring contraction reaction is a pretty neat trick using a thallium reagent published by University of Basel in Switzerland and University of Sao Paulo in Brazil by Andreas Pfaltz and Luiz Silva and co-workers in JOC.

ttn-reaction


JOC paper

A review on ring contractions by Silva can be found in TL:
TL Review
ring contraction

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Posted in New Types, Sesquiterpenes | Leave a Comment »

A Tandem Hydroalkoxylation-Hydroarylation Reaction

Posted by naturalproductman on February 7, 2009

Francisco J. Fananas at the Universidad de Oviedo in Spain has recently published a synthesis on bruguierol A, which is a natural product that shows modest antimicrobial activity.  The activity is okay, but the way they made the bicyclic ring system is really neat and worth checking out.

bruguierol A

The JOC paper here

Isolation paper

Posted in New Types | Leave a Comment »