Naturalproductman’s Blog

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Archive for the ‘Peptides’ Category

Coprisamides A and B

Posted by naturalproductman on February 22, 2015

Dong-Chan Oh and co-workers from Seoul National University have reported in Organic Letters on the isolation of coprisamides A and B from gut bacteria of beetles.

coprisamides

OL paper

Posted in Peptides | Leave a Comment »

Jahanyne

Posted by naturalproductman on January 17, 2015

Kiyotake Suenaga and co-workers from Keio University have reported in Organic Letters on the isolation of jahanyne.

lipopeptide
OL paper

Posted in Apoptosis, Peptides | Leave a Comment »

Lysocin E synthesis

Posted by naturalproductman on December 15, 2014

Masayuki Inoue and co-workers have reported in ACIE on the synthesis of lysocin E.

peptide

ACIE paper

Posted in Peptides, Total Synthesis | Leave a Comment »

Mannopeptimycin aglycone synthesis

Posted by naturalproductman on August 18, 2014

Takayuki Doi and co-workers at Tohoku University have reported in JACS on the synthesis of mannopeptimycin aglycone.

mannopeptimycin aglycone

JACS paper

Posted in Aldol, Methodology, Peptides | Leave a Comment »

1-Alaninechlamydocin

Posted by naturalproductman on July 15, 2014

Robert Cichewicz and co-workers from the University of Oklahoma have reported in the Journal of Natural Products on the isolation of a tetrapeptide with HDAC inhibitory activity. This compound was isolated from a fungus in Lake Superior.

peptide

JNP paper

Posted in Cancer, Histone deacetylase, Peptides, Protein Targets | Leave a Comment »

Polyketide-peptide hybrid

Posted by naturalproductman on June 28, 2014

Liangcheng Du and co-workers at University of Nebraska-Lincoln have reported in ACIE on a polyketide synthase–nonribosomal peptide synthetase that made a hybrid polyketide-peptide compound.

polyketide

ACIE paper

Posted in Chemical Biology, Hybrids, Peptides, Polyketides | Leave a Comment »

Stellatolides

Posted by naturalproductman on May 6, 2014

Carmen Cuevas and co-workers from PharmaMar in Spain have reported in JACS on the isolation and syntheses of stellatolides.

stellatolides

JACS paper

Posted in Cancer, Depsipeptides, Peptides, Total Synthesis | Leave a Comment »

Luciferin from earthworms

Posted by naturalproductman on April 18, 2014

Ilia Yampolsky and co-workers at the Russian Academy of Sciences have reported in ACIE on the isolation of luciferin from the luminous earthworm.

 

ACIE paper

Posted in Peptides, Polyenes | Leave a Comment »

MA026 synthesis

Posted by naturalproductman on December 9, 2013

Fumio Sugawara and co-workers at the Tokyo University of Science have reported in JACS on the synthesis of MA026 and its anti-hepatitis C virus activity.

HCV

JACS paper

Posted in Anti-viral, Diseases, Hepatitis C, Peptides, Total Synthesis | Leave a Comment »

Echinocandin C synthesis

Posted by naturalproductman on April 23, 2013

Markus Oberthür and colleague at Philipps-Universität Marburg reported in ACIE on the synthesis of echinocandin C.

echinocandin C

ACIE paper

Posted in Methodology, Peptides | Leave a Comment »

 
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