Naturalproductman’s Blog

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Archive for the ‘Polyketides’ Category

Tetracycline analogs

Posted by naturalproductman on February 22, 2015

Hrvoje Petkovic and co-workers at University of Ljubljana have reported in ACIE on a biosynthetic engineering approach to produce new tetracycline compounds.

tetracycline

ACIE paper

Posted in Biosynthesis, Chemical Biology, Polyketides, Tetracycline | Leave a Comment »

Brazilin synthesis

Posted by naturalproductman on January 18, 2015

Ikyon Kim and colleague from Yonsei University have reported in JOC on the synthesis of brazilin.

brazilin

JOC paper

Posted in Polyketides, Total Synthesis | Leave a Comment »

Trioxacarcin DC-45-A2 synthesis

Posted by naturalproductman on January 17, 2015

KC Nicolaou and co-workers have reported in ACIE on the synthesis of trioxacarcin DC-45-A2. polyketide ACIE paper

Posted in Polyketides, Total Synthesis | Leave a Comment »

Aglaiastatin synthesis

Posted by naturalproductman on January 17, 2015

John Porco and co-workers have reported in JACS on the synthesis of aglaiastatin.
aglaiastatin
JACS paper

Posted in Asymmetric, Methodology, Polyketides, Total Synthesis | Leave a Comment »

Tiacumicin B (Lipiarmycin A3/Fidaxomicin) aglycone synthesis

Posted by naturalproductman on December 15, 2014

Karl Heinz-Altmann and co-workers at ETH Zurich have reported in ACIE on the synthesis of fidaxomicin aglycone.

fidaxomicin

ACIE paper

Posted in Macrolides, Polyenes, Polyketides, Total Synthesis | Leave a Comment »

Leucosceptroids A and B syntheses

Posted by naturalproductman on December 6, 2014

Dawei Ma and co-workers have reported in ACIE on the synthesis of leucosceptroids A and B.

A and B

ACIE paper

Posted in Polyketides, Total Synthesis | Leave a Comment »

Kushecarpin A synthesis

Posted by naturalproductman on December 6, 2014

Thomas Pettus and co-workers have reported in ACIE on the syntheses of some polyketides related to kushecarpin A.

kushecarpin A

ACIE paper

Posted in Polyketides, Total Synthesis, Unified | Leave a Comment »

Hippolachnin A synthesis

Posted by naturalproductman on December 6, 2014

Erick Carreira and co-workers have reported in ACIE on the synthesis of hippolachnin A.
synthesis
ACIE paper

Posted in Methodology, Polyketides, Total Synthesis | Leave a Comment »

Cochliomycin synthesis via NHK

Posted by naturalproductman on November 29, 2014

Martin Banwell and co-workers at the Australian National University have reported in JOC on the synthesis of cochliomycins A and B.

cochliomycins

JOC paper

Posted in cross coupling, Macrolides, Metathesis, Methodology, Named Reactions, Polyketides, Total Synthesis | Leave a Comment »

Lipiarmycin synthesis

Posted by naturalproductman on November 28, 2014

Jieping Zhu and co-workers at CNRS EPFL-SB-ISIC-LSPN have reported in ACIE on the synthesis of lipiarmycin.

polyketide

ACIE paper

Posted in Glycosides, Methodology, Polyketides, Total Synthesis | 2 Comments »

 
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