Naturalproductman’s Blog

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Archive for the ‘Ion channels’ Category

Saxitoxin analogs and biological activities

Posted by naturalproductman on September 18, 2011

Kazuo Nagasawa and co-workers at Tokyo University of Agriculture and Technology have reported in Chemistry a European Journal on the synthesis of saxitoxin analogs and their biological activities towards sodium ion channels.


Chemistry a European Journal paper

Posted in Alkaloids, Chemical Biology, Ion channels, Methodology, Proteins, Unnatural Products | Leave a Comment »

Progesterone Activity towards Human Sperm

Posted by naturalproductman on March 18, 2011

Here’s a Nature paper by Yuriy Krichok and co-workers at UCSF on the effect of progesterone onto the Ca2+ ion channel in human sperm – interestingly this response is not found in mouse sperm.

Nature paper

Posted in Chemical Biology, Ion channels, Proteins | Leave a Comment »