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Archive for the ‘Spirocycles’ Category

Cipacinoids

Posted by naturalproductman on January 19, 2016

Jian-Min Yue and co-workers from the Chinese Academy of Sciences have reported in Organic Letters on the isolation of cipacinoids A-D, which had protein tyrosine phosphatase 1B inhibition (17 micromolar).

 

OL paper

Posted in Diabetes Type 2, Spirocycles, Spirocyclic centers | Leave a Comment »

Asymmetric spiroketalization

Posted by naturalproductman on October 29, 2015

Seijiro Matsubara and co-workers at Kyoto University have reported in ACIE on the use of an aminothiourea catalyst to form spiroketals asymmetrically.

amino

ACIE paper

Posted in Asymmetric, Methodology, Organocatalytic, Spirocycles | Leave a Comment »

Corynoxine synthesis

Posted by naturalproductman on December 18, 2014

Chengfeng Xia and co-workers from the Chinese Academy of Sciences have reported in JACS on the syntheses of corynoxine.

corynoxine

JACS paper

Posted in Alkaloids, Cascade Reactions, Spirocycles, Total Synthesis | Leave a Comment »

Varioxepine A

Posted by naturalproductman on August 28, 2014

Bin-Gui Wang and co-workers from the Chinese Academy of Sciences have reported in Organic Letters on the isolation of an interesting oxepine containing alkaloid.

oxepine

OL paper

Posted in Alkaloids, Oxepines, Spirocycles | Leave a Comment »

Gymnothelignan N synthesis

Posted by naturalproductman on August 18, 2014

Xuegong She and co-workers from Lanzhou University have reported in Organic Letters on the synthesis of

Friedel-Crafts

OL paper

Posted in Friedel-Crafts, Named Reactions, Spirocycles, Spirocyclic centers, Total Synthesis | Leave a Comment »

Cyanogramide

Posted by naturalproductman on July 15, 2014

Weiming Zhu and co-workers at Ocean University of China have reported in Organic Letters on the isolation of cyanogramide.

cyanogramide

OL paper

Posted in Alkaloids, Cancer, Spirocycles | Leave a Comment »

Colletoic acid synthesis

Posted by naturalproductman on February 20, 2013

Masahisa Nakada and co-worker from Waseda University have reported in Org Lett on a synthesis of colletoic acid.

synthesis

OL paper

Posted in Carboxylic acids, Spirocycles, Total Synthesis | Leave a Comment »

Mycosporulone synthesis

Posted by naturalproductman on September 7, 2012

Michael Jung and colleague at UCLA have reported in Organic Letters on the synthesis of mycosporulone.

mycosporulone

OL paper

Posted in Aldol, Asymmetric, Methodology, Named Reactions, Polyketides, retro-Aldol, Spirocycles, Total Synthesis | Leave a Comment »

Abiestetranes A and B

Posted by naturalproductman on August 6, 2012

Wei-Dong Zhang and co-workers from have reported in Tetrahedron on the isolation of some spirocyclic tetraterpenes, abiestetranes A and B.

tetraterpenes

Tetrahedron paper

Posted in Cancer, Spirocycles, Terpenes | Leave a Comment »

Chipericumins A–D

Posted by naturalproductman on November 10, 2011

Jun’ichi Kobayashi and co-workers from Hokkaido University have reported in the Journal of Natural Products on the isolation of some acylphloroglucinols.

acylphloroglucinols

JNP paper

Posted in Glucinols, Spirocycles | Leave a Comment »