Antonio Echavarran and co-workers from ICIQ have reported in ACIE on the synthesis of cannabimovone.
Posted by naturalproductman on May 29, 2016
Antonio Echavarran and co-workers from ICIQ have reported in ACIE on the synthesis of cannabimovone.
Posted in alkyne, Cascade Reactions, Gold, Methodology, Structural Reassignment, Total Synthesis | Leave a Comment »
Posted by naturalproductman on March 31, 2016
Seth Herzon and co-workers from Yale have reported in JACS on the synthesis of precolibactin. It’s another example of why total synthesis is important. But another interesting aspect about this natural product is that previous efforts used bioinformatics approaches to propose the thiazoline-thiazole chain – when in fact the natural product has a terminal cysteine appended where this thiazoline-thiazole chain was proposed to exist.
Posted in Biosynthesis, Peptides, Structural Reassignment, Total Synthesis | Leave a Comment »
Posted by naturalproductman on November 24, 2015
Hao Xu’s lab in University of Georgia have reported on an iron-catalyzed diazidation of olefins.
Dorian Didier’s lab from LMU Munich reported on an interesting one-pot reaction.
Posted in Cascade Reactions, Hypervalent Iodine, Methodology, Structural Reassignment, Total Synthesis | Leave a Comment »
Posted by naturalproductman on October 15, 2015
Wu Su and co-workers from the Chinese Academy of Sciences have reported in JACS on the synthesis of coibamide A.
Posted in Macrocycles, Peptides, Structural Reassignment, Total Synthesis | Leave a Comment »
Posted by naturalproductman on August 21, 2015
Karl Hale and colleague at the Queen’s University Belfast have reported in Organic Letters on the synthesis of mycothiazole.
Posted in Alkaloids, Methodology, Structural Reassignment, Thiazoles, Total Synthesis | Leave a Comment »
Posted by naturalproductman on July 17, 2015
Masayuki Inoue and co-workers from the University of Tokyo have reported in JACS on the synthesis of yaku’amide.
Posted in Peptides, Structural Reassignment | Leave a Comment »
Posted by naturalproductman on May 4, 2015
Posted in Macrolides, Structural Reassignment, Total Synthesis | Leave a Comment »
Posted by naturalproductman on April 16, 2015
Jeroen Disckschat and co-workers at Rheinische Friedrich-Wilhelms-Universität Bonn have reported in ACIE on a 13C-13C COSY method to elucidate the structure of hypodoratoxide.
Posted in Methodology, New Setups, Structural Reassignment | Leave a Comment »
Posted by naturalproductman on April 12, 2015
Rongbiao Tong and colleague from the Hong Kong University of Science and Technology have reported in Organic Letters on the synthesis of uprolide F diacetate.
Posted in Structural Reassignment, Total Synthesis | Leave a Comment »
Posted by naturalproductman on November 16, 2014
Rosario Hernández-Galán and co-workers at Universidad de Cádiz in Spain have reported in JOC on the synthesis of cinbotolide and the revised structure through total synthesis looks completely different from the proposed macrocyclic structure.
Posted in Structural Reassignment, Total Synthesis | Leave a Comment »