Naturalproductman’s Blog

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Archive for the ‘Total Synthesis’ Category

Muironolide A synthesis

Posted by naturalproductman on May 4, 2015

Armen Zakarian and co-workers have reported in JACS on the synthesis of muironolide A.

muironolide A

JACS paper

Posted in Macrolides, Structural Reassignment, Total Synthesis | Leave a Comment »

Gelsemoxonine synthesis

Posted by naturalproductman on May 4, 2015

Erick Carreira and colleague have reported in JACS on the synthesis of gelsemoxonine.

alkaloid

JACS paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Serpentine synthesis

Posted by naturalproductman on May 2, 2015

Karl Scheidt and co-workers have reported in ACIE on the synthesis of alstonine and serpentine through cooperative catalysis.
heteroyohimbine
ACIE paper

Posted in Alkaloids, Cooperative Catalysis, Methodology, Total Synthesis | Leave a Comment »

Mycoleptodiscin A synthesis

Posted by naturalproductman on April 26, 2015

Ang Li and co-workers from SIOC have reported in ACIE on the synthesis of mycoleptodiscin A.

mycoleptodiscin
ACIE paper

Posted in Alkaloids, Steroids, Total Synthesis | Leave a Comment »

Eudistidine A

Posted by naturalproductman on April 20, 2015

The NCI does some nice work with natural products. Kirk Gustafson and co-workers at Bethesda have reported in JACS on some new natural products that block the interaction between p300 and HIF1alpha.

70

JACS paper

Posted in Alkaloids, Protein-Protein Interaction, Proteins, Total Synthesis | Leave a Comment »

Steenkrotin A synthesis

Posted by naturalproductman on April 18, 2015

Huanfeng Ding and co-workers from Zhejiang University have reported in ACIE on the synthesis of steenkrotin A.

steenkrotin A

ACIE paper

Posted in Diterpenoids, Methodology, Radical Chemistry, Total Synthesis | Leave a Comment »

Ouabagenin synthesis

Posted by naturalproductman on April 17, 2015

Masayuki Inoue and co-workers from the University of Tokyo have reported in Chemical Science on the synthesis of ouabagenin.

 
ouabagenin
Chemical Science paper

Posted in Steroids, Total Synthesis | Leave a Comment »

Tunicamycin synthesis

Posted by naturalproductman on April 16, 2015

Biao Yu and colleague at SIOC have reported in ACIE on the synthesis of tunicamycin.

tunicamycin

ACIE paper

Posted in Glycosides, Total Synthesis | Leave a Comment »

5,6-Dihydrocineromycin B synthesis

Posted by naturalproductman on April 16, 2015

Alois Furstner and co-workers have reported in ACIE on the synthesis of 5,6-dihydrocineromycin B.
lactone
ACIE paper

Posted in cross coupling, Macrolides, Named Reactions, Total Synthesis | Leave a Comment »

Uprolide F diacetate

Posted by naturalproductman on April 12, 2015

Rongbiao Tong and colleague from the Hong Kong University of Science and Technology have reported in Organic Letters on the synthesis of uprolide F diacetate.
uprolide

OL paper

Posted in Structural Reassignment, Total Synthesis | Leave a Comment »

 
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