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Archive for the ‘Total Synthesis’ Category

Harringtonolide

Posted by naturalproductman on August 23, 2016

Hongbin Zhai and co-workers from Peking University have reported in ACIE on the synthesis of harringtonolide through a [3+2] reaction.

 

ACIE paper

Posted in Diterpenoids, Total Synthesis | Leave a Comment »

Spinosyn A synthesis

Posted by naturalproductman on August 22, 2016

Mingji Dai and co-workers at Purdue reported in JACS on the synthesis of spinosyn A through a carbonylative macrolactonization.

 

JACS paper

Posted in Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Cochlearenine, N-Ethyl-1α-hydroxy-17-veratroyldictyzine, and Paniculamine syntheses

Posted by naturalproductman on August 22, 2016

Richmond Sarpong and co-workers reported in JACS on the synthesis of paniculamine.

 

JACS paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Psiguadial B synthesis

Posted by naturalproductman on August 2, 2016

Sarah Reisman and co-workers have reported in JACS on the synthesis of psiguadial B. The key step was a Wolff rearrangement using a Honeywell UV lamp. The supporting information has a nice picture of the reaction set up. It looks like you just shine the lamp next to the reaction flask with aluminum foil around it.

 

JACS paper

Posted in Total Synthesis, Wolff rearrangement | Leave a Comment »

Synthesis of hamigerans

Posted by naturalproductman on July 31, 2016

Shuanhu Gao and co-workers at East China Normal University have reported in ACIE on the synthesis of hamigerans.

 

ACIE paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Notoamide synthesis

Posted by naturalproductman on July 30, 2016

Chaozhong Li and co-workers at SIOC reported in ACIE on the synthesis of notoamides F, R, and I.

 

ACIE paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Exochomine synthesis

Posted by naturalproductman on July 30, 2016

Scott Snyder and co-workers have reported in ACIE on the synthesis of exochomine.

 

ACIE paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Juglorescein and Juglocombins A and B synthesis

Posted by naturalproductman on July 30, 2016

Kouji Kuramochi and co-workers from Tokyo University of Science have reported in ACIE on the synthesis of juglorescein.

 

ACIE paper

Posted in Polyketides, Total Synthesis | Leave a Comment »

Hyperjapones A-E synthesis

Posted by naturalproductman on July 30, 2016

Jonathan George and co-workers from the University of Adelaide have reported in ACIE on the synthesis of hyperjapones A-E.

 

ACIE paper

Posted in Total Synthesis | Leave a Comment »

Chiral Anion Phase Transfer (CAPT)

Posted by naturalproductman on July 30, 2016

Dean Toste and co-workers have reported in JACS on the enantioselective synthesis of flavonoids using CAPT.

 

JACS paper

Posted in Asymmetric, Polyketides, Total Synthesis | Leave a Comment »

 
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