Naturalproductman’s Blog

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Archive for the ‘Total Synthesis’ Category

Oridamycin synthesis

Posted by naturalproductman on July 22, 2015

Another solo performance from Danishefsky’s lab published by Adam Trotta.

OL paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

Penibruguieramine A synthesis

Posted by naturalproductman on July 22, 2015

Sanghee Kim and co-workers from Seoul National University have reported in ACIE on the synthesis of penibruguieramine A.

alkaloid

ACIE paper

Posted in Alkaloids, Asymmetric, Kinetic resolution, Methodology, Total Synthesis | Leave a Comment »

Hosieine A synthesis

Posted by naturalproductman on July 22, 2015

Ran Hong and co-workers at SIOC have reported in ACIE on the synthesis of hosieine A. The pyridone moiety reminds of lyconadin.

alkaloid

ACIE paper

Posted in Alkaloids, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »

Englerin A synthesis

Posted by naturalproductman on July 20, 2015

Shunichi Hashimoto and co-workers from Hokkaido University have reported in Chemistry a European Journal on their total synthesis of englerin A.

Chemistry – a European Journal paper

Posted in Sesquiterpenes, Total Synthesis | Leave a Comment »

Xylapyrrosides A and B

Posted by naturalproductman on July 13, 2015

Jin-Feng Hu and co-workers from Fudan University have reported in Tetrahedron on the isolation and synthesis of xylapyrrosides.
xylapyrrosides

Tetrahedron paper

Posted in Antioxidants, Spiroketals, Total Synthesis | Leave a Comment »

Cycloprodigiosin synthesis

Posted by naturalproductman on July 11, 2015

Richmond Sarpong and co-workers have reported in Organic Letters on the synthesis of cyclopropdiogisin. It’s an ACS Editor’s Choice article! Good job!

cycloprodigiosin

OL paper

Posted in Alkaloids, Pyrroles, Total Synthesis | Leave a Comment »

Staphyloferrin B synthesis

Posted by naturalproductman on July 11, 2015

Elizabeth Nolan and co-workers from MIT have reported in JACS on the synthesis of staphyloferrin B, an iron chelating natural product found in bacteria.

iron

JACS paper

Posted in Chemical Biology, Peptides, Total Synthesis | Leave a Comment »

Guanacastepene syntheses

Posted by naturalproductman on July 11, 2015

Chin-Kang Sha and colleague from National Tsing-Hua University have reported in Organic Letters on the syntheses of guanacastapenes N and O.

guanacastepene

OL paper

Posted in Copper, Diels-Alder, Kinetic resolution, Methodology, Named Reactions, Radical Chemistry, Sesquiterpenes, Total Synthesis, Transition Metal | Leave a Comment »

Debromohamigeran E synthesis

Posted by naturalproductman on July 3, 2015

James Morken and colleague at Boston College have reported in JACS on the synthesis of debromohamigeran E.
boron
JACS paper

Posted in cross coupling, Methodology, Total Synthesis | Leave a Comment »

Shishijimicin A synthesis

Posted by naturalproductman on July 3, 2015

Nicolaou and co-workers at Rice University have reported in JACS on the synthesis of shishijimicin.
shishijimicin A
 

JACS paper

Posted in Total Synthesis | Leave a Comment »

 
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