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Archive for the ‘Total Synthesis’ Category

Palau’amine synthesis

Posted by naturalproductman on April 28, 2016

Here’s another total synthesis of palau’amine by Keiji Tanino and co-workers from Hokkaido University. I can’t believe I missed it.

 

Nature Communications paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

(−)-Terengganensine A synthesis

Posted by naturalproductman on April 20, 2016

Jieping Zhu and co-workers have reported in ACIE on the synthesis of (−)-terengganensine A.

 

ACIE paper

Posted in Alkaloids, Indoles, Total Synthesis | Leave a Comment »

(−)-Deschloromytilipin A and (−)-Danicalipin A

Posted by naturalproductman on April 8, 2016

Noah Burns and co-workers from Stanford have reported in JACS on the syntheses of (−)-deschloromytilipin A and (−)-danicalipin A.

 

JACS paper

Posted in Chlorosulpholipids, Halogenated, Lipids, Methodology, Total Synthesis | Leave a Comment »

Towards puberuline C

Posted by naturalproductman on April 8, 2016

Masayuki Inoue and co-workers reported in Chemical Science on a synthesis of the hexacycle of puberuline C.

 

Chemical Science paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

(−)-Daphenylline synthesis

Posted by naturalproductman on April 8, 2016

Tohru Fukuyama and co-workers have reported in ACIE on the synthesis of (−)-daphenylline.

 

ACIE paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

ent-Ascospiroketals A and B syntheses

Posted by naturalproductman on April 7, 2016

Rongbiao Tong and colleague from Hong Kong University of Science and Technology have reported in Organic Letters on the synthesis of ascospiroketals A and B.

 

OL paper

Posted in Cascade Reactions, Polyketides, Total Synthesis | Leave a Comment »

Helicascolide syntheses

Posted by naturalproductman on April 5, 2016

Bernhard Breit and co-workers from Albert-Ludwigs-Universität Freiburg have reported in ACIE on the synthesis of helicascolides A, B, and C.

 

ACIE paper

Posted in Methodology, Polyketides, Total Synthesis | Leave a Comment »

Hydroxygardnerine, Hydroxygardnutine, Gardnerine, (E)-16-epi-Normacusine B, and Koumine syntheses

Posted by naturalproductman on April 4, 2016

Hiromitsu Takayama and co-workers from Chiba University have reported in Organic Letters on the syntheses of some indole alkaloids using a gold catalyzed 6-exo dig cyclization – which looks like a Conia-ene reaction.

 

OL paper

Posted in Alkaloids, Conia-Ene, Gold, Indoles, Named Reactions, Total Synthesis, Transition Metal | Leave a Comment »

Phorbol synthesis

Posted by naturalproductman on March 31, 2016

Phil Baran and co-workers reported in Nature on a synthesis of phorbol – in 19 steps.

 

Nature paper

Posted in Diterpene, Total Synthesis | Leave a Comment »

Aspidodasycarpine and Lonicerine syntheses

Posted by naturalproductman on March 31, 2016

Ang Li and co-workers reported in JACS on the synthesis of aspidodasycarpine and lonicerine.

 

JACS paper

Posted in Alkaloids, Total Synthesis | Leave a Comment »

 
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