Naturalproductman’s Blog

Hey, is that a natural product?!

Blue-LED induced cascade

Posted by naturalproductman on July 17, 2015

Zhiyong Jiang and co-workers from Henan University have reported in ACIE on a radical cascade cyclization using blue light emitted diodes.

radical

ACIE paper

Posted in Cascade Reactions, Light Mediated, Methodology, Radical Chemistry | Leave a Comment »

Pyridinium catalyzed glycosylation

Posted by naturalproductman on July 17, 2015

Albrecht Berkessel and co-workers at Cologne University have reported in ACIE on a pyridinium catalyzed glycosylation reaction.
pyridinium
ACIE paper

Posted in Cascade Reactions, Methodology, Organocatalytic | Leave a Comment »

Alpha-bisabolol

Posted by naturalproductman on July 15, 2015

Victoriano Corpas-Lopez and co-workers at Universidad de Granada have reported in Journal of Natural Products on the use of alpha-bisabolol as a treatment for visceral leishmaniasis.

JNP paper

Posted in Diseases | Leave a Comment »

C-C bond cleavage of alpha-aryl acetals

Posted by naturalproductman on July 13, 2015

Thomas Lectka and co-workers from Johns Hopkins University have reported in Chemical Science on an interesting C-C bond cleavage process.

C-C

Chemical Science paper

Posted in C-C Bond Breaking, Cascade Reactions, Light Mediated, Methodology | Leave a Comment »

On the utility of allenoates

Posted by naturalproductman on July 13, 2015

Hongchao Guo and co-workers from China Agricultural University have reported in Chemical Communications on a [4+1] cyclization of allenoates with anilines to form substituted indolines.

4+1

Chem Comm paper

Posted in Allenes, Cascade Reactions, Methodology | Leave a Comment »

Xylapyrrosides A and B

Posted by naturalproductman on July 13, 2015

Jin-Feng Hu and co-workers from Fudan University have reported in Tetrahedron on the isolation and synthesis of xylapyrrosides.
xylapyrrosides

Tetrahedron paper

Posted in Antioxidants, Spiroketals, Total Synthesis | Leave a Comment »

Newman-Kwart reaction mechanism

Posted by naturalproductman on July 13, 2015

Hafize Ozcan and co-workers from Trakya University in Turkey have reported in Tetrahedron on an interesting mechanistic investigation of the Newman-Kwart reaction.

Newman-Kwart

Tetrahedron paper

Posted in Cascade Reactions, Computational, DFT, Electrocyclization, Mechanistic, Methodology, Named Reactions, Newman-Kwart, Sigmatropic Rearrangements | Leave a Comment »

Sarglabolides A-K

Posted by naturalproductman on July 13, 2015

Long-Yi Kong and co-workers from China Pharmaceutical University have reported in Tetrahedron on the isolation of sarglabolides that inhibited NO production (2.33 micromol/L).

sarglabolides

Tetrahedron paper

Posted in Dimer, Sesquiterpenes | Leave a Comment »

Pauson-Khand followed by a radical cyclization to yield a propellanone

Posted by naturalproductman on July 13, 2015

Laura Peterson and co-workers have reported in Tetrahedron on a molecule that looks like a propeller.
propeller
Tetrahedron paper

Posted in Cascade Reactions, Methodology, Named Reactions, Radical Chemistry | Leave a Comment »

Cycloprodigiosin synthesis

Posted by naturalproductman on July 11, 2015

Richmond Sarpong and co-workers have reported in Organic Letters on the synthesis of cyclopropdiogisin. It’s an ACS Editor’s Choice article! Good job!

cycloprodigiosin

OL paper

Posted in Alkaloids, Pyrroles, Total Synthesis | Leave a Comment »

 
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