Naturalproductman’s Blog

Hey, is that a natural product?!

Rhodium and triazoles cascade

Posted by naturalproductman on April 16, 2015

When I saw this paper I thought of the stuff Dale Boger does with the triazole cascade reactions.

triazole

ACIE paper

Posted in Cascade Reactions, Methodology, Transition Metal | Leave a Comment »

Tunicamycin synthesis

Posted by naturalproductman on April 16, 2015

Biao Yu and colleague at SIOC have reported in ACIE on the synthesis of tunicamycin.

tunicamycin

ACIE paper

Posted in Glycosides, Total Synthesis | Leave a Comment »

5,6-Dihydrocineromycin B synthesis

Posted by naturalproductman on April 16, 2015

Alois Furstner and co-workers have reported in ACIE on the synthesis of 5,6-dihydrocineromycin B.
lactone
ACIE paper

Posted in cross coupling, Macrolides, Named Reactions, Total Synthesis | Leave a Comment »

C-H Activation Cascade

Posted by naturalproductman on April 16, 2015

Kevin Booker Millburn and colleague at the University of Bristol have reported in ACIE on a palladium C-H activation cascade reaction.

C-H
ACIE paper

Posted in C-H activation, Cascade Reactions, Methodology, Palladium, Transition Metal | Leave a Comment »

Uprolide F diacetate

Posted by naturalproductman on April 12, 2015

Rongbiao Tong and colleague from the Hong Kong University of Science and Technology have reported in Organic Letters on the synthesis of uprolide F diacetate.
uprolide

OL paper

Posted in Structural Reassignment, Total Synthesis | Leave a Comment »

Gold catalyzed spiroketalization

Posted by naturalproductman on April 12, 2015

Aaron Aponick and co-workers from the University of Florida have used a trimethylphosphine additive to improve the gold catalyzed spiroketalization for spirastrellolide.

gold

OL paper

Posted in Diastereoselective, Gold, Methodology, Regioselective, Transition Metal | Leave a Comment »

Solanioic acid

Posted by naturalproductman on April 12, 2015

Raymond Anderson and co-workers from the University of British Columbia have reported in Organic Letters on the isolation of solanioic acid.
solanoic acid
OL paper

Posted in Steroids | Leave a Comment »

Gamma-hydroxylation

Posted by naturalproductman on April 12, 2015

Chi-Sing Lee and co-workers from Peking University have reported in Organic Letters on a gamma-hydroxylation of an enone to access phomactin C.

phomactin C

OL paper

Posted in Named Reagents | Leave a Comment »

Galanthamine and lycoramine syntheses

Posted by naturalproductman on April 12, 2015

Yanxing Jia and co-workers at Peking University have reported in ACIE on the synthesis galanthamine and lycoramine.
galanthamine

ACIE paper

Posted in Alkaloids, Asymmetric, Methodology, Total Synthesis, Transition Metal | Leave a Comment »

Alkyne + Formic Acid = Vinyl carboxylic acid

Posted by naturalproductman on April 12, 2015

Qi-Lin Zhou and co-workers from Nankai University have reported in ACIE on a palladium catalyzed hydrocarboxylation of alkynes.

Pd

ACIE paper

Posted in Methodology, Palladium, Transition Metal | Leave a Comment »

 
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