N. P. Dhammika Nanayakkara and co-workers from the University of Mississippi have reported in JNP on the isolation of some compounds that look like BINAP.
Archive for April, 2012
No that’s not BINAP
Posted by naturalproductman on April 25, 2012
Posted in Aromatic, C2-Symmetric | Leave a Comment »
Angelone synthesis
Posted by naturalproductman on April 25, 2012
Zhigang Weng and co-workers from Shenzhen University have reported in Tetrahedron on a synthesis of angelone. The highlight is the cascade reaction forming the final product.
Posted in Aromatic, Cascade Reactions, Mechanistic, Methodology, One pot, Total Synthesis | Leave a Comment »
Streptocarbazoles
Posted by naturalproductman on April 25, 2012
Weiming Zhu and co-workers at the Ocean University of China have reported in Organic Letters on the isolation of streptocarbazoles A and B.
Posted in Alkaloids, Cancer | Leave a Comment »
Rhizopodin synthesis
Posted by naturalproductman on April 24, 2012
Dirk Menche and co-workers from Universität Heidelberg have reported in ACIE on the synthesis of rhizopodin.
Posted in C2-Symmetric, Macrolides, Methodology, Oxazoles, Total Synthesis | Leave a Comment »
Selective macrocyclization
Posted by naturalproductman on April 23, 2012
Christopher Boddy and co-workers at the University of Ottawa have reported in Organic Letters on the selective macrocyclization using DEBS TE.
Posted in Chemical Biology, Enzymatic, Macrocycles, Macrolides, Methodology | Leave a Comment »
Psoromic acid inhibits RabGGTase
Posted by naturalproductman on April 23, 2012
Yao-Wen Wu and co-workers at Max Planck have reported in JACS on the inhibition of RabGGTase using psoromic acid.
Posted in Aromatic, Cancer, Carboxylic acids, Post-Translational Modification, Protein Targets | Leave a Comment »