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Archive for the ‘Asthma’ Category

Africanan-1alpha-ol synthesis

Posted by naturalproductman on November 11, 2011

Douglass Taber and co-workers from the University of Delaware have reported in JOC on the synthesis of trans-africanan-1alpha-ol. The synthesis of the seven membered ring was achieved from a relay-ring closing metathesis reaction.  The synthesized structure does not seem to match the reported structure.


JOC paper

Posted in Asthma, Cascade Reactions, Diseases, Metathesis, Methodology, Ruthenium, Sesquiterpenes, Seven-Membered Rings, Structural Reassignment, Total Synthesis, Transition Metal | Leave a Comment »