Anthony Barrett and co-workers at Imperial College have reported in Organic Letters on a cascade reaction that involves the formation of a ketene followed by trapping with an enamine to form pyridinones.
Archive for the ‘Claisen condensation’ Category
Ketene cascade
Posted by naturalproductman on September 18, 2011
Posted in Cascade Reactions, Claisen condensation, Diels-Alder, Methodology, Named Reactions, Transition Metal, Zinc | Leave a Comment »
Reformatsky-Claisen Cascade
Posted by naturalproductman on November 19, 2010
Jeffrey Johnson and co-workers at UNC have published in JACS on a Refoormatzky-Claisen condensation cascade reaction where the second enolate generated opens a beta-lactone.
Posted in Cascade Reactions, Claisen condensation, Methodology, Multi-Component Coupling, Named Reactions, Reformatsky, Ring Opening, Transition Metal, Zinc | Leave a Comment »