Posted by naturalproductman on September 18, 2011
Anthony Barrett and co-workers at Imperial College have reported in Organic Letters on a cascade reaction that involves the formation of a ketene followed by trapping with an enamine to form pyridinones.
Posted in Cascade Reactions, Claisen condensation, Diels-Alder, Methodology, Named Reactions, Transition Metal, Zinc | Leave a Comment »
Posted by naturalproductman on November 19, 2010
Jeffrey Johnson and co-workers at UNC have published in JACS on a Refoormatzky-Claisen condensation cascade reaction where the second enolate generated opens a beta-lactone.
Posted in Cascade Reactions, Claisen condensation, Methodology, Multi-Component Coupling, Named Reactions, Reformatsky, Ring Opening, Transition Metal, Zinc | Leave a Comment »