Erick Carreira and colleague have reported in ACIE on the synthesis of pallambin.
Archive for July, 2015
Pallambins A and B syntheses
Posted by naturalproductman on July 31, 2015
Posted in Electrocyclization, Methodology, Total Synthesis | Leave a Comment »
Cannizzaro cascade
Posted by naturalproductman on July 30, 2015
Simon Woodward and co-workers have reported in ACIE on a Cannizzaro cascade reaction using tert-butyl lithium.
ACIE paper
Posted in Cascade Reactions, Methodology, Multi-Component Coupling | Leave a Comment »
Oridamycin synthesis
Posted by naturalproductman on July 22, 2015
Another solo performance from Danishefsky’s lab published by Adam Trotta.
Posted in Alkaloids, Total Synthesis | Leave a Comment »
What kind of heterocycles are in drugs?
Posted by naturalproductman on July 22, 2015
This is a good review by Jon Njardarson and co-workers in Journal of Medicinal Chemistry on the analysis of heterocycles in FDA approved drugs.
JMC paper
Posted in Medicinal Chemistry | Leave a Comment »
Penibruguieramine A synthesis
Posted by naturalproductman on July 22, 2015
Sanghee Kim and co-workers from Seoul National University have reported in ACIE on the synthesis of penibruguieramine A.
Posted in Alkaloids, Asymmetric, Kinetic resolution, Methodology, Total Synthesis | Leave a Comment »
Hosieine A synthesis
Posted by naturalproductman on July 22, 2015
Ran Hong and co-workers at SIOC have reported in ACIE on the synthesis of hosieine A. The pyridone moiety reminds of lyconadin.
Posted in Alkaloids, Cascade Reactions, Methodology, Total Synthesis | Leave a Comment »
Englerin A synthesis
Posted by naturalproductman on July 20, 2015
Shunichi Hashimoto and co-workers from Hokkaido University have reported in Chemistry a European Journal on their total synthesis of englerin A.
Posted in Sesquiterpenes, Total Synthesis | Leave a Comment »