Naturalproductman’s Blog

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Archive for the ‘Sesterterpenes’ Category

Erinacine S

Posted by naturalproductman on February 2, 2016

Chien-Chang Shen and co-workers from Hung Kuang University and National Yang-Ming University in Taiwan have reported in the Journal of Natural Products on the isolation of erinacine S, which had increased the expression of an insulin-degrading enzyme in the cerebral cortex.

JNP paper

Posted in Diabetes Type 1, Diabetes Type 2, Diseases, Sesterterpenes | Leave a Comment »

Phyllospongin D has a cyclobutane

Posted by naturalproductman on January 18, 2015

Rabab Mohammed and co-workers from Beni-Suef University in Egypt have reported in Tetrahedron on the isolation of some sesterterpenes from an Egyptian marine sponge.


Tetrahedron paper

Posted in Sesterterpenes | Leave a Comment »

Schisanwilsonene A synthesis

Posted by naturalproductman on May 10, 2013

Antonio Echavarran and co-workers at ICIQ have reported in ACIE on a synthesis of schisanwilsonene A.


ACIE paper

Posted in Methodology, Sesterterpenes, Seven-Membered Rings, Total Synthesis | Leave a Comment »

Looks like guanacastepene

Posted by naturalproductman on May 7, 2013

Asperterpenols A and B were isolated from a mangrove fungus.


OL paper

Posted in Sesterterpenes, Sesterterpenoids | Leave a Comment »

Not just isolating small molecules anymore…

Posted by naturalproductman on January 17, 2013

Hideaki Oikawa and co-workers from Hokkaido University have reported in Organic Letters on the isolation of an enzyme that was known to produce some natural products. They expressed and purified the enzyme, incubated the enzyme in the presence of substrates:  geranyl diphosphate (GPP) and isopentenyl diphosphate (IPP), and examined the products.

sesterterpene synthase

OL paper

Posted in Chemical Biology, Enzymes, Methodology, Proteins, Sesterterpenes | Leave a Comment »