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Archive for the ‘Allenes’ Category

Reactions involving the use, synthesis, intermediates of allenes.

Chiral phosphoric acid for allenamides with ketones

Posted by naturalproductman on January 29, 2016

Dean Toste and colleague have reported in Chemical Science on the use of a chiral phosphoric acid catalyst to react allenamides with ketones. I guess the papers published in Chemical Science in 2015 and 2016 are all open access.

 

Chemical Science paper

Posted in Allenes, Methodology, Organocatalytic | Leave a Comment »

Back to Back Method Papers: Allenamide + Aldehyde = alpha-Alkylation

Posted by naturalproductman on January 22, 2016

Fernando Lopez and co-workers at Universidad de Santiago de Compostela have reported in Chemical Communications on a gold/organocatalyst-cocatalyzed alpha alkylation of aldehydes. Interestingly Jose Gonzalez and co-workers at Universidad de Oviedo also reported in Chem Comm on a gold/organocatalyst reaction.

 

Chem Comm paper

 

Chem Comm paper 2

Posted in Allenes, Asymmetric, Cascade Reactions, Cooperative Catalysis, Gold, Methodology, Organocatalytic, Transition Metal | Leave a Comment »

Clavosolide A synthesis

Posted by naturalproductman on November 10, 2015

Bernhard Breit and colleague at Albert-Ludwigs-Universität Freiburg have reported in ACIE on a synthesis of clavosolide, taking advantage of the C2 symmetry.

C2

ACIE paper

Posted in Allenes, C2-Symmetric, Cascade Reactions, Glycosides, Methodology, Total Synthesis | Leave a Comment »

Alkynyl trifluoroborate + aldehyde = allene

Posted by naturalproductman on November 2, 2015

Regan Thomson and co-workers from Northwestern report in ACS Combinatorial Science on a traceless Petasis reaction.

Petasis

ACS Combinatorial Science paper

Posted in Allenes, Cascade Reactions, Methodology, Named Reactions | Leave a Comment »

Kumausallene synthesis

Posted by naturalproductman on October 9, 2015

Chepuri Ramana and colleague have reported in Tetrahedron on a formal synthesis of kumausallene.
kumausallene

Tetrahedron paper

Posted in Allenes, Methodology, Total Synthesis | Leave a Comment »

On the utility of allenoates

Posted by naturalproductman on July 13, 2015

Hongchao Guo and co-workers from China Agricultural University have reported in Chemical Communications on a [4+1] cyclization of allenoates with anilines to form substituted indolines.

4+1

Chem Comm paper

Posted in Allenes, Cascade Reactions, Methodology | Leave a Comment »

Alkaloid 205B synthesis

Posted by naturalproductman on February 10, 2015

Jin Kun Cha and colleague at Wayne State University have reported in JACS on a synthesis of alkaloid 205B.

205

JACS paper

Posted in Alkaloids, Allenes, Methodology, Total Synthesis | Leave a Comment »

Silacarboxylation of allenes

Posted by naturalproductman on December 6, 2014

Yasushi Tsuji and co-workers have reported in JACS on a copper catalyzed silacarboxylation of allenes using carbon dioxide and a silylborane.

JACS paper

Posted in Allenes, Copper, Methodology, Transition Metal | Leave a Comment »

Allenyl gold complexes

Posted by naturalproductman on September 8, 2014

Concepcion Gimeno and co-workers from ISQCH in Spain have reported in JACS on an allenyl gold complex. I wonder how they would react with electrophiles.

allenyl gold

JACS paper

Posted in Allenes, Gold, Methodology, Transition Metal | Leave a Comment »

Crinipellin A synthesis

Posted by naturalproductman on July 12, 2014

Hee-Yoon Lee and co-workers at KAIST have reported in JACS on the synthesis of crinipellin A.

synthesis

JACS paper

Posted in Allenes, Methodology, Total Synthesis | Leave a Comment »

 
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