Raymond Andersen and co-workers reported in JOC on the isolation of nahuoic acid. They used Rychnovsky’s method to determine the relative stereochemistry of the alcohols.
Archive for the ‘Classical rules’ Category
Nahuoic acid
Posted by naturalproductman on February 3, 2016
Posted in Cancer, Classic papers, Classical rules, Polyketides, Protein Targets, Rycnovsky's rules | Leave a Comment »
Allylboration through Z-T TS
Posted by naturalproductman on May 6, 2014
Kalman Szabo and coworkers from Stockholm University have reported in Chemical Science on an allylboration selective for the anti-product, which can be explained by the Zimmerman-Traxler transition state.
Posted in Classical rules, Methodology, Zimmerman-Traxler transition state | Leave a Comment »
Rules are made to be broken
Posted by naturalproductman on May 6, 2014
Craig Williams and co-workers from the University of Queensland have reported in ACIE on the isolation of EBC-219, a diterpene possessing a bridge head olefin.
Posted in Bredt's, Classical rules, Diterpene | Leave a Comment »
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