Clavosolide synthesis

Varinder Aggarwal and co-workers at the University of Bristol reported in ACIE on the synthesis of clavosolide.

 

ACIE paper

Huperzine A synthesis

James White and co-workers have reported in Organic Letters on the synthesis of huperzine A.

OL paper

Indium bromide cyclization

Teck-Peng Loh and co-workers from the University of Science and Technology have reported in ACIE on the synthesis of moluccanic acid methyl ester through a Prins-polyene cyclization using indium (III) bromide.

ACIE paper

Portentol via Prins

Pierre van de Weghe and co-workers at Université de Rennes have reported in Organic Letters on their progress towards portentol using a Prins reaction.

OL paper

 

Oxidative Prins-pinacol

Sylvain Canesi and co-workers at Université du Québec à Montréal have reported in JOC on an oxidative Prins-pinacol approach towards platensimycin.

JOC paper

Aspergillin PZ synthesis

Larry Overman and co-workers have reported in Tetrahedron on the synthesis of aspergillin PZ using a tin mediated Prins-pinacol reaction.

Tetrahedron paper

Exiguolide synthesis

Karl Scheidt and co-workers at Northwestern have reported in ACIEE on their synthesis of exiguolide and you guessed it:  Prins cyclization was used to form the tetrahydropyran rings.

ACIEE paper

Friedel-Crafts/Prins to get haouamine

Jeffrey Aube and co-workers at Kansas have reported in Organic Letters on their approach to haouamine via a Friedel Crafts/Prins sequence.

OL paper

Okilactomycin synthesis

Karl Scheidt and co-workers at Northwestern have reported in ACIEE on the synthesis of okilactomycin using a Prins cyclization to access the tetrahydropyran structure.

ACIEE paper

Scabronine G synthesis

Yoshiharu Iwabuchi and co-workers at Tohoku University have reported in Organic Letters on the total synthesis of scabronine G.

OL paper