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Archive for the ‘Polyenes’ Category

Molecular prosthetics

Posted by naturalproductman on August 7, 2015

Martin Burke’s group is making use of their small molecules that they’re synthesizing.
prosthetic
JACS paper

Posted in Chemical Biology, Macrolides, Methodology, Polyenes, Polyketides | Leave a Comment »

Tiacumicin B (Lipiarmycin A3/Fidaxomicin) aglycone synthesis

Posted by naturalproductman on December 15, 2014

Karl Heinz-Altmann and co-workers at ETH Zurich have reported in ACIE on the synthesis of fidaxomicin aglycone.

fidaxomicin

ACIE paper

Posted in Macrolides, Polyenes, Polyketides, Total Synthesis | Leave a Comment »

Amphirionin-4

Posted by naturalproductman on September 8, 2014

Masashi Tsuda and co-workers from Kochi University have reported in Organic Letters on the isolation of amphirionin-4.

amphirionin-4

OL paper

Posted in Polyenes | Leave a Comment »

Delta12-prostaglandin J3 synthesis

Posted by naturalproductman on August 18, 2014

Nicolaou and co-workers have reported in ACIE on the synthesis of delta12-prostaglandin J3.

prostaglandin J3

ACIE paper

Posted in Aldol, Cancer, leukemia, Methodology, Polyenes, Prostaglandins, Total Synthesis | Leave a Comment »

Lipomycin synthesis

Posted by naturalproductman on June 28, 2014

Reinhard Brückner and colleague at Albert-Ludwigs-Universität Freiburg have reported in ACIE on the synthesis of lipomycin.

lipomycin

ACIE paper

Posted in Polyenes, Total Synthesis | Leave a Comment »

Luciferin from earthworms

Posted by naturalproductman on April 18, 2014

Ilia Yampolsky and co-workers at the Russian Academy of Sciences have reported in ACIE on the isolation of luciferin from the luminous earthworm.

 

ACIE paper

Posted in Peptides, Polyenes | Leave a Comment »

Heronamides

Posted by naturalproductman on April 1, 2014

Hideaki Kakeya and co-workers from Kyoto University have reported in JACS on the isolation and activity of heronamides.

heronamides

JACS paper

Posted in Macrolactams, Polyenes | Leave a Comment »

13-Demethyllyngbyaloside B synthesis

Posted by naturalproductman on March 20, 2013

Haruhiko Fuwa and co-workers from Tohoku University have reported in Organic Letters on a synthesis of 13-demethyllyngbyaloside B.

macrolide

OL paper

Posted in Macrolides, Methodology, Polyenes, Total Synthesis | Leave a Comment »

Ajudazol B synthesis

Posted by naturalproductman on November 16, 2012

Dirk Menche and co-workers from the Universitat Bonn have reported in Organic Letters on a synthesis and stereochemical assignment from a bioinformatics study.

synthesis

JACS paper

Posted in Asymmetric, Bioinformatics, Computational, Methodology, Oxazoles, Polyenes | Leave a Comment »

Light mediated rearrangement of natural products

Posted by naturalproductman on November 12, 2012

Yoshito Kishi and co-workers have published in JACS on the photochemistry of mycolactone A and B.

light

JACS paper

Similarly Hong-Xiang Lou and co-workers at Shandong University have published in JACS on the light induced interconversion of pallambins.

pallambins

OL paper

Posted in Light Mediated, Methodology, Polyenes | Leave a Comment »

 
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