Naturalproductman’s Blog

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Archive for August, 2013

Plectosphaeroic acid C syntheses

Posted by naturalproductman on August 30, 2013

Larry Overman and colleague have reported in JOC on a synthesis of plectosphaeroic acid C.

polythiol

JOC paper

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Posted in Alkaloids, Methodology, Total Synthesis | Leave a Comment »

Spirooliganones A and B

Posted by naturalproductman on August 30, 2013

Shi-Shan Yu and co-workers from the Institute of Materia Medica have reported in Organic Letters on the isolation of spirooliganones A and B.

spirooliganones A and B

OL paper

Posted in Anti-viral | Leave a Comment »

Limazepine E synthesis

Posted by naturalproductman on August 30, 2013

Ronalds Zemribo and colleague at the Latvian Institute of Organic Chemistry have reported in Org Lett on a an Ireland-Claisen rearrangement approach to synthesizing limazepine E and barmumycin.

limazepine E

OL paper

Posted in Alkaloids, Cascade Reactions, Ireland-Claisen rearrangement, Methodology, Named Reactions, Pericyclic reactions, Sigmatropic Rearrangements | Leave a Comment »

Benzyne intermediate

Posted by naturalproductman on August 30, 2013

Akkattu Biju and co-workers from CSIR have reported in Org Lett on a multi-component reaction involving a benzyne intermediate.

benzyne

OL paper

Posted in Cascade Reactions, Methodology, Multi-Component Coupling | Leave a Comment »

Azepine access

Posted by naturalproductman on August 30, 2013

Jin-Heng Li and co-workers from Hunan University have reported in ACIE on a silver catalyzed method to yield azepine derivatives.

azepine

ACIE paper

Posted in Cascade Reactions, Methodology, Silver, Transition Metal | Leave a Comment »

Aza-Pauson Khand reaction

Posted by naturalproductman on August 30, 2013

Chisato Mukai and co-workers at Kanazawa University have reported in ACIE on an aza-Pauson Khand reaction.

aza

ACIE paper

Posted in Cascade Reactions, Methodology, Named Reactions, Pauson-Khand, Rhodium, Transition Metal | Leave a Comment »

Silyl Heck reaction

Posted by naturalproductman on August 30, 2013

Donald Watson and colleague have reported in JACS on silyl Heck variant.

vinyl silyl ethers

JACS paper

Posted in cross coupling, Heck, Methodology, Palladium, Transition Metal | Leave a Comment »

Voattingine and Tabertinggine

Posted by naturalproductman on August 30, 2013

Toh-Seok Kham and co-workers at Malaya University have reported in Org Lett on some indole alkaloids.

indole

OL paper

Posted in Alkaloids, Indoles | Leave a Comment »

Asymmetric gold catalysis

Posted by naturalproductman on August 30, 2013

Huw Davies and colleague have reported in JACS on an asymmetric gold catalyzed [3+2] reaction.

3+2

JACS paper

Posted in Asymmetric, Cascade Reactions, Gold, Methodology, Transition Metal | Leave a Comment »

(−)-Aspidospermidine, (−)-Tabersonine, and (−)-Vincadifformine syntheses

Posted by naturalproductman on August 30, 2013

Rodrigo Andrade and colleague at Temple University have reported in JACS on a cascade synthesis of some aspidosperma alkaloids.

aspidosperma

JACS paper

Posted in Alkaloids, Cascade Reactions, Methodology, Organocatalytic, Total Synthesis | Leave a Comment »