Hideo Kigoshi and co-workers from the University of Tsukuba have reported in ACIE on the synthesis of mycalolides.
Archive for the ‘Metathesis’ Category
Mycalolides synthesis
Posted by naturalproductman on October 9, 2015
Posted in Macrocycles, Metathesis, Methodology, Oxazoles, Ruthenium, Total Synthesis | Leave a Comment »
Pseudotabersonine via double ring closing metathesis
Posted by naturalproductman on August 19, 2015
Stephen Martin and co-workers reported in Tetrahedron on the synthesis of pseudotabersonine using a double ring closing metathesis approach.
Posted in Alkaloids, Metathesis, Methodology, Ruthenium, Total Synthesis, Transition Metal | Leave a Comment »
Ru-catalyzed metathesis of fluoro-olefins and enol ethers
Posted by naturalproductman on June 6, 2015
Yusuke Takahira and colleague at Asahi Glass Co. have reported in JACS on a cross metathesis between fluoro-olefins and enol ethers.
Posted in Metathesis, Ruthenium, Transition Metal | Leave a Comment »
Disorazole synthesis through metathesis
Posted by naturalproductman on May 2, 2015
Alison Hulme and co-workers from the University of Edinburgh have reported in ACIE on a metathesis approach to disorazole. Reminds me of the Hoveyda approach.
Posted in Asymmetric, C2-Symmetric, Metathesis, Methodology, Molybdenum, Transition Metal | Leave a Comment »
A Formal Metathesis
Posted by naturalproductman on April 16, 2015
Zhang Jie-Shi and co-workers from the Chinese Academy of Sciences have reported in JACS on a rhodium catalyzed exchange between an aryl keton and an aryl carboxylic acid to form aliphatic carboxylic acids and biaryl compounds.
Posted in Cascade Reactions, Metathesis, Methodology, Rhodium, Transition Metal | Leave a Comment »
Cochliomycin synthesis via NHK
Posted by naturalproductman on November 29, 2014
Martin Banwell and co-workers at the Australian National University have reported in JOC on the synthesis of cochliomycins A and B.
Posted in cross coupling, Macrolides, Metathesis, Methodology, Named Reactions, Polyketides, Total Synthesis | Leave a Comment »
Neopeltolide through metathesis
Posted by naturalproductman on November 8, 2014
Hoveyda and co-workers have reported in ACIE on the synthesis of neopeltolide.
Posted in Metathesis, Methodology, Ruthenium, Total Synthesis, Transition Metal | Leave a Comment »
Disorazole through cross metathesis
Posted by naturalproductman on November 8, 2014
Hoveyda and co-workers from Boston College have reported in JACS on a Z-selective cross coupling to access this C2-symmetric molecule – using alkenyl boronate and alkenyl iodide moieties.
Posted in Alkaloids, C2-Symmetric, Metathesis, Methodology, Oxazoles, Ruthenium, Transition Metal | Leave a Comment »
Cascade metathesis towards humulanolides
Posted by naturalproductman on October 4, 2014
Chuang-Chuang Li and co-workers at the University of Science and Technology have reported in JACS on a cascade metathesis approach to the synthesis of humulanolides.
Posted in Cascade Reactions, Humulanolides, Metathesis, Methodology | Leave a Comment »
Asymmetric metathesis
Posted by naturalproductman on September 8, 2014
Grubbs and colleagues have reported in JACS on their studies with asymmetric ring closing metathesis.
Posted in Asymmetric, Cascade Reactions, Metathesis, Methodology, Ring Opening | 1 Comment »