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Archive for the ‘Oxadiazoles’ Category

Phidianidines

Posted by naturalproductman on April 20, 2011

Margerhita Gavagnin and co-workers from Consiglio Nazionale delle Ricerche (CNR) in Italy have reported in Organic Letters on the isolation of some 1,2,4-oxadiazoles dubbed phidianidines from the marine opisthobranch mollusk Phidiana militaris.  Phidinidine A had an IC50 value of 1.52 micromolar against HeLa cells.

phidianidines

OL paper

Posted in Alkaloids, Cancer, Oxadiazoles | Leave a Comment »