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Archive for the ‘Dotz benzannulation’ Category

Arizonin C1 synthesis

Posted by naturalproductman on July 3, 2011

Reinhard Bruckner and co-workers at Universitat Freiburg have reported in the European JOC on their synthesis of arizonin C1.

arizonin C1

European JOC paper

Posted in Cascade Reactions, Dotz benzannulation, Knoevenagel condensation, Methodology, Named Reactions, Pictet-Spengler, Total Synthesis, Transition Metal | Leave a Comment »

Kendomycin Synthesis

Posted by naturalproductman on March 13, 2010

Masaya Nakata and co-workers at Keio University have recently published in Organic Letters on an approach for kendomycin.  The key reaction was a macrocyclization of a chromium carbene complex with an alkyne, also known as the Dotz benzannulation.

OL paper

Posted in Cascade Reactions, Chromium, Dotz benzannulation, Macrocycles, Methodology, Named Reactions, Transition Metal | Leave a Comment »