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Archive for the ‘Norditerpenes’ Category

Towards harringtonolide

Posted by naturalproductman on June 2, 2011

Bastien Nay and co-workers from UMR have reported in Tetrahedron Letters on their progress towards harringtonolide.


TL paper

Posted in Methodology, Norditerpenes | Leave a Comment »

Synthesis of Caribenol A

Posted by naturalproductman on September 10, 2010

Zhen Yang and co-workers at Peking University have published in JACS on the total synthesis of caribenol via an intramolecular Diels-Alder reaction using an activated alkyne as the dienophile.  The intramolecular Diels-Alder reaction required the use of a catalytic amount of 2,6-di-tert-butyl-4-methylphenol (BHT) – an antioxidant.

Diels Alder

JACS paper

Posted in Antibiotics, Cascade Reactions, Cycloaddition, Diels-Alder, Methodology, Named Reactions, Norditerpenes, Pericyclic reactions, Ring forming, Seven-Membered Rings | Leave a Comment »