Three component coupling

Masayuki Inoue and co-workers from University of Tokyo have reported in Organic Letters on a three component Pummerer reaction using V-40 [1,10-azobis(cyclohexane-1-carbonitrile)].

OL paper

Pummerer-type Lactonization

Apparao Satyam and co-worker at Piramal Life Sciences Limited have reported in Tetrahedron Letters on a vinylogous Pummerer reaction.

TL paper

Unexpected Epoxidation

Danishefsky and co-workers have published in JACS on an epoxidation of a substrate with an olefin tethered by a sulfoxide.

 

JACS paper

Lyconadin A Synthesis

Fukuyama and co-workers have published in JACS on a total synthesis of lyconadin A.

JACS paper

Benzofurans from Phenols

Koichiro Oshima and co-workers at Kyoto University have published in JACS on a Pummerer reaction with the key reagent being a trifluoromethyl ketene dithioacetal monoxide.

JACS paper

Synthesis of Ent-Hyperforin

Masakatsu Shibasaki and co-workers at the University of Tokyo have recently published in ACIEE on the total synthesis of ent-hyperforin, a polyprenylated acylphloroglucinol.  One of the key reactions was an asymmetric Diels-Alder cycloaddition that involved the use of a cationic iron complex using a chiral pybox ligand.

ACIEE paper