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Archive for the ‘Nazarov cyclization’ Category

Nazarov-semipinacol cascade

Posted by naturalproductman on July 11, 2015

Take a cyclobutanol bearing dienone and see what kind of Nazarov reaction occurs…Yong-Qiang Tu and co-workers at Lanzhou University reported in JACS on this interesting asymmetric transformation.

Nazarov

JACS paper

Posted in Asymmetric, Cascade Reactions, Methodology, Named Reactions, Nazarov cyclization, Organocatalytic | Leave a Comment »

Nazarov in the presence of KMnO4

Posted by naturalproductman on July 10, 2015

From Frederick G. West’s lab at the University of Alberta: potassium permanganate was present in a Nazarov reaction and an interesting C-C bond cleavage reaction occured.
Nazarov
ACIE paper

Posted in Cascade Reactions, Methodology, Named Reactions, Nazarov cyclization | Leave a Comment »

Rocaglamide synthesis

Posted by naturalproductman on March 31, 2015

Marcus Tius and colleague have reported in ACIE on the asymmetric synthesis of rocaglamide.
rocaglamide

ACIE paper

Posted in Asymmetric, Named Reactions, Nazarov cyclization, Total Synthesis | Leave a Comment »

Aza-Nazarov

Posted by naturalproductman on November 29, 2014

G Sekar and co-workers from IIT Madras have reported in Chem Comm on an aza-Nazarov cyclization.

Chem Comm paper

Posted in Electrocyclization, Methodology, Named Reactions, Nazarov cyclization | Leave a Comment »

Interrupted Nazarov

Posted by naturalproductman on October 7, 2014

FG West and co-workers from the University of Alberta have reported in an Nazarov cyclization study combining DFT and experiment to explain the diastereoselectivity.

 

 

JACS paper

Posted in Cascade Reactions, Methodology, Named Reactions, Nazarov cyclization | Leave a Comment »

Tetrapetalone A-Me glycon synthesis

Posted by naturalproductman on July 12, 2014

Alison Frontier and co-workers at Rochester University and Hoveyda Boston College have reported in ACIE on the synthesis of tetrapetalone A-Me glycon.

tetrapetalone

 

ACIE paper

Posted in Alkaloids, Methodology, Named Reactions, Nazarov cyclization, Total Synthesis | Leave a Comment »

Gracilamine synthesis

Posted by naturalproductman on July 12, 2014

Shuanhu Gao and co-workers at East China Normal University have reported in ACIE on the synthesis of gracilamine.
alkaloid

ACIE paper

 

Posted in Alkaloids, Mannich, Methodology, Michael, Named Reactions, Nazarov cyclization, Total Synthesis | Leave a Comment »

Imino-Nazarov reaction

Posted by naturalproductman on November 8, 2012

Richard Hsung and co-workers published in Org Lett on an imino Nazarov reaction catalyzed by gold and silver.

imino Nazarov

OL paper

Posted in Cascade Reactions, Gold, Methodology, Named Reactions, Nazarov cyclization, Transition Metal | Leave a Comment »

Cascade Nazarov

Posted by naturalproductman on November 7, 2012

Carlos Saa and co-workers at Universidad de Santiago de Compostela in Spain have reported in ACIE on a cascade Nazarov reaction.

Nazarov

ACIE paper

Posted in Cascade Reactions, Methodology, Named Reactions, Nazarov cyclization | Leave a Comment »

Another Nazarov? Or not.

Posted by naturalproductman on August 31, 2012

Zhang-Jie Shi and co-workers at Peking University have reported in Organic Letters on a palladium catalyzed cyclization process, which at first glance looked like it may be a Nazarov reaction but they proved that it probably is not a Nazarov reaction because of the observed kinetic isotope effect when they replaced the aryl hydrogens with deuteriums.

no not a Nazarov

OL paper

Posted in Cascade Reactions, Electrocyclization, Methodology, Named Reactions, Nazarov cyclization, Palladium, Pericyclic reactions, Transition Metal | Leave a Comment »

 
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