Srivari Chandrasekhar and co-workers at Indian Institute of
Chemical Technology have reported in Chemistry – a European Journal on their progress towards allopumiliotoxins.
Archive for the ‘Indolizidines’ Category
Dienamine cyclization
Posted by naturalproductman on January 24, 2012
Ryan Shenvi and co-workers from Scripps have reported in JACS on a cyclization of a dienamine.
Posted in Cascade Reactions, Indolizidines, Methodology | 1 Comment »
Michael followed by Pictet-Spengler
Posted by naturalproductman on August 29, 2011
Xiaoyu Wu and co-workers at Shanghai University have reported in Chemistry a European Journal on a reaction that involves two named reaction using an indole tethered with a primary amine and an alkynoate as the subtrates.
Posted in Cascade Reactions, Indoles, Indolizidines, Methodology, Michael, Named Reactions, Organocatalytic, Pictet-Spengler | Leave a Comment »
Flueggines A and B
Posted by naturalproductman on July 5, 2011
Wen-Cai Ye and co-workers at Jinan University have reported in Organic Letters on the isolation of flueggines A and B. Flueggine B had activity with an IC50 values of 135 ± 5 and 147 ± 3 nM against MCF-7 and MDA-MB-231 cells, respectively.
Posted in Alkaloids, breast, Cancer, Indoles, Indolizidines, Isoxazolidines | Leave a Comment »