Hyocholic Acid from Chenodeoxycholic Acid and a New Derivatization Method

The Yoshimoto research lab at UTSA published in Steroids on a synthesis of hyocholic acid, the bile acid that is high in cases with less diabetes. The study finishes off with a derivatization method using sodium meta-periodate to cleave the C6-C7 bond of the B-ring. This method was used to identify new hyocholic acid derivatives found in ox bile, which has been used to treat diabetes type II symptoms in the past.

Steroids paper