SARS CoV-2 update

Here’s an update on a biochemical perspective of SARS CoV-2 proteins (especially the spike protein).

The Protein Journal

Proteins of SARS CoV-2

Francis Yoshimoto published a review in The Protein Journal on the proteins from SARS CoV-2, the virus that caused COVID-19, the current global pandemic. There is no question that natural products will play a role in understanding SARS CoV-2 and potentially be used as a therapeutic to treat this disease.

The Protein Journal paper

Pestaloxazine A

Chang-Lun Shao and co-workers from the Ocean University of China have reported in Organic Letters on the isolation of anti-viral pestaloxazine A.

OL paper

ZMapp vs. ebola

Gary Kopinger and co-workers from the University of Manitoba have reported in Nature on ZMapp’s reversion of the ebola virus.
Nature paper

Sweriledugenin A

Ji-Jun Chen and co-workers at the Kunming Institute of Botany have reported in Org Lett on the isolation of sweriledugenin A.

OL paper

MA026 synthesis

Fumio Sugawara and co-workers at the Tokyo University of Science have reported in JACS on the synthesis of MA026 and its anti-hepatitis C virus activity.

JACS paper

Spirooliganones A and B

Shi-Shan Yu and co-workers from the Institute of Materia Medica have reported in Organic Letters on the isolation of spirooliganones A and B.

OL paper