Herbal medicine is not always the answer

Aristolochic acid, a compound found in Chinese medicine, is carcinogenic.

Environmental Toxicology and Pharmacology paper

Amphidinolide V synthesis

Daesung Lee and colleague have reported in JACS on a synthesis of amphidinolide V.

 

JACS paper

Yaku’amide A synthesis

Masayuki Inoue and co-workers from the University of Tokyo have reported in JACS on the synthesis of some peptides, yaku’amide A.

JACS paper

13-Demethyllyngbyaloside B synthesis

Haruhiko Fuwa and co-workers from Tohoku University have reported in Organic Letters on a synthesis of 13-demethyllyngbyaloside B.

OL paper

Gold catalyzed [2+2]

Antonio Echavarren and co-workers from ICIQ in Spain have reported in Org Lett on a gold catalyzed intramolecular [2+2] between an alkene and alkyne.

OL paper

Garuganin and garugamblin syntheses

Chris Beaudry and co-workers at Oregon State have reported in JOC on some syntheses of diaryl heptanoids.

JOC paper

Asymmetric aminoboration of alkenes

Masahiro Miura and co-workers from Osaka University have reported in JACS on an olefin difunctionalization.

JACS paper

Good presentations

Here’s an editorial on the importance of presentations.

Triyne to aromatic ring

Daesung Lee and co-workers at the University of Illinois in Chicago have reported in JACS on a silver promoted cascade involving a C-H insertion from a silver catalyzed aryne formation.

JACS paper

Iron catalyzed [2+2]

Paul Chirik and co-workers from Princeton have reported in JACS on a mechanistic study of an iron catalyzed [2+2].

JACS paper