Naturalproductman’s Blog

Hey, is that a natural product?!

Archive for March, 2013

Herbal medicine is not always the answer

Posted by naturalproductman on March 28, 2013

Aristolochic acid, a compound found in Chinese medicine, is carcinogenic.

Environmental Toxicology and Pharmacology paper

Posted in Carcinogens | Leave a Comment »

Amphidinolide V synthesis

Posted by naturalproductman on March 22, 2013

Daesung Lee and colleague have reported in JACS on a synthesis of amphidinolide V.

 

JACS paper

Posted in Macrolides, Methodology, Total Synthesis | Leave a Comment »

Yaku’amide A synthesis

Posted by naturalproductman on March 22, 2013

Masayuki Inoue and co-workers from the University of Tokyo have reported in JACS on the synthesis of some peptides, yaku’amide A.

JACS paper

Posted in Cancer, leukemia, Methodology, Peptides, Total Synthesis | Leave a Comment »

13-Demethyllyngbyaloside B synthesis

Posted by naturalproductman on March 20, 2013

Haruhiko Fuwa and co-workers from Tohoku University have reported in Organic Letters on a synthesis of 13-demethyllyngbyaloside B.

macrolide

OL paper

Posted in Macrolides, Methodology, Polyenes, Total Synthesis | Leave a Comment »

Gold catalyzed [2+2]

Posted by naturalproductman on March 20, 2013

Antonio Echavarren and co-workers from ICIQ in Spain have reported in Org Lett on a gold catalyzed intramolecular [2+2] between an alkene and alkyne.

[2+2]

OL paper

Posted in Cycloaddition, Gold, Methodology, Pericyclic reactions, Transition Metal, [2+2] | Leave a Comment »

Garuganin and garugamblin syntheses

Posted by naturalproductman on March 20, 2013

Chris Beaudry and co-workers at Oregon State have reported in JOC on some syntheses of diaryl heptanoids.

heptanoids

JOC paper

Posted in Asymmetric, Heptanoids, Mechanistic, Methodology, Structural Reassignment, Total Synthesis | Leave a Comment »

Chiral allene synthesis

Posted by naturalproductman on March 20, 2013

Doug Frantz and co-workers at UT San Antonio have reported in JACS on a palladium catalyzed asymmetric approach to synthesizing axially chiral allenes through beta-hydride elimination.

allene

JACS paper

Posted in Allenes, Asymmetric, Methodology, Palladium, Transition Metal | Leave a Comment »

Asymmetric aminoboration of alkenes

Posted by naturalproductman on March 20, 2013

Masahiro Miura and co-workers from Osaka University have reported in JACS on an olefin difunctionalization.

olefin

JACS paper

Posted in Asymmetric, Cascade Reactions, Copper, Methodology, Transition Metal | Leave a Comment »

Good presentations

Posted by naturalproductman on March 19, 2013

Here’s an editorial on the importance of presentations.

Posted in Random | Leave a Comment »

Triyne to aromatic ring

Posted by naturalproductman on March 15, 2013

Daesung Lee and co-workers at the University of Illinois in Chicago have reported in JACS on a silver promoted cascade involving a C-H insertion from a silver catalyzed aryne formation.

aryne

JACS paper

Posted in Cascade Reactions, Methodology, Silver, Transition Metal | Leave a Comment »