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Archive for the ‘Polypodanes’ Category

Myrrhanol A

Posted by naturalproductman on July 6, 2009

Alejandro Barrero at the University of Granada in Spain and co-workers have recently published in JOC on the synthesis of an anti-inflammatory agent,  myrrhanol A.  A key step in the synthesis was the reaction they used to make the 6,6-scaffold of the molecule, which involved a cascade titanium mediated bis-olefin epoxide opening cyclization.


JOC link

Posted in Cascade Reactions, cross coupling, Methodology, Polypodanes, Ring forming, Transition Metal, Triterpenes | 2 Comments »