Naturalproductman’s Blog

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Archive for the ‘Prostaglandins’ Category

Prostaglandin E2 methyl ester synthesis

Posted by naturalproductman on February 15, 2016

Minoru Isobe and co-workers from National Tsing Hua University have reported in JOC on a synthesis of PGE2 methyl ester using a very nice cascade cyclization.

PGE methyl ester Isobe JOC


JOC paper

Posted in Cascade Reactions, Prostaglandins, Total Synthesis | Leave a Comment »

Delta12-prostaglandin J3 synthesis

Posted by naturalproductman on August 18, 2014

Nicolaou and co-workers have reported in ACIE on the synthesis of delta12-prostaglandin J3.

prostaglandin J3

ACIE paper

Posted in Aldol, Cancer, leukemia, Methodology, Polyenes, Prostaglandins, Total Synthesis | Leave a Comment »