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Archive for the ‘Tetrahydropyrans’ Category

Oxetane to tetrahydropyran

Posted by naturalproductman on January 20, 2016

Jeannie Sun and colleague at the Hong Kong University of Science and Technology have reported in ACIE on an intramolecular Sn2 reaction to convert a symmetrical oxetane ring to a tetrahydropyran.

 

ACIE paper

Posted in Asymmetric, Cascade Reactions, Methodology, Tetrahydropyrans | Leave a Comment »

LmbF is a PLP-enzyme

Posted by naturalproductman on October 21, 2015

Jiri Janata and co-workers from ASCR in the Czech Republic have reported in Chemical Science on the identification of the enzyme, LmbF, in the biosynthesis of lincomycin.

lincomycin

Chemical Science paper

Posted in Alkaloids, Biosynthesis, Chemical Biology, Tetrahydropyrans | Leave a Comment »