Combining chemical and enzymatic synthesis

Kevin Reynolds and co-workers from Portland State University have reported in JOC on the synthesis of premarineosin analogs using a chemo-enzymatic approach.

JOC paper

Dibromoalkenes from alkynes

Weimin He and co-workers from Hunan University have reported in JOC on the synthesis of E-dibromoalkenes from alkynes using CuBr2.

JOC paper

Propargylamines via multi-component approach

Zhihua Sun and co-workers from the Shanghai University of Engineering Science have reported in JOC on a multicomponent approach to substituted propargylamines.

JOC paper

Cochliomycin synthesis via NHK

Martin Banwell and co-workers at the Australian National University have reported in JOC on the synthesis of cochliomycins A and B.

JOC paper

Perophoramidine synthesis

Barry Trost and co-workers have reported in Chemical Science on the synthesis of perophoramidine.

Chemical Science paper

Aza-Nazarov

G Sekar and co-workers from IIT Madras have reported in Chem Comm on an aza-Nazarov cyclization.

Chem Comm paper

Pyridinium leaving group

Philip Albiniak and colleagues at Ball State University have reported in Tetrahedron Letters on the synthesis of tert-butyl ethers using a pyridinium leaving group.

TL paper

Multi-component coupling with cobalt

Xiaobing Wan and co-workers from Soochow University have reported in ACIE on a multi-component coupling approach to access β-Ester-γ-amino ketones.

ACIE paper

N-Tosyl hydrazones to alkynes with copper

Huanfeng Jiang and co-workers from South China University of Technology have reported in ACIE on a copper catalyzed conversion of N-tosyl hydrazones to alkynes. The problem is I don’t know how regioselective this is.

ACIE paper

Lipiarmycin synthesis

Jieping Zhu and co-workers at CNRS EPFL-SB-ISIC-LSPN have reported in ACIE on the synthesis of lipiarmycin.

ACIE paper