Diaryl Ethers from Hypervalent Iodines

Berit Olofsson and co-workers at Stockholm University have reported in Organic Letters on a hypervalent iodine approach to access diaryl ethers.

 

OL paper

Vinylogous Michael

Alexandre Alexakis and co-workers at Universite de Geneve in Switzerland have reported in Organic Letters on a vinylogous Michael reaction.

OL paper

 

Lactones make enolate surrogates

Akira Yanagisawa and co-workers at Chiba University have reported in Organic Letters on the use of β,γ-didehydro-γ-lactone as tin-enolate precursors to effect an Aldol reaction.

 

OL paper

Austocystin D and MDR1

Henry Pelish and co-workers at Makoto Life Sciences have reported in the Journal Natural Products on the compound, austocystin D, which gets activated by a cytochrome P450 enzyme (CYP3A4) and then does the damage to the cells.

 

JNP paper

Bronstead Acid Catalyzed Cyclization

Magnus Rueping and co-workers at RWTH Aachen University have reported in JACS on a Bronsted acid catalyzed cyclization of a phenol with an ortho-allylic alcohol substituent to form the ring.

 

JACS paper

[1,5]-Sigmatropic Hydrogen Shift

Yong-Min Liang and co-workers at Lanzhou University have reported in JOC on a palladium catalyzed 1,5-sigmatropic hydrogen shift to form naphthylamine substrates.

 

JOC paper

Cyclobutenones from Allenoates

Shengming Ma and co-workers at Zhejiang University have reported in JACS on the usefulness of allenoates – you can make cyclobutenones.

 

JACS paper

Furans to Spiroketals via Singlet Oxygen

Georgios Vassilikogiannakis and co-workers from the University of Crete report on the light induced spirocyclization reaction of a furan.

OBC paper

Ageliferin Progress

Carl Lovely and co-workers at UT Arlington have reported in Organic and Biomolecular Chemistry on their progress towards ageliferin via an intramolecular Diels-Alder reaction.

OBC paper

Iodine to Fluorinate

Kazunori Miyamoto and co-workers at the University of Tokushima have reported in Chem Comm on the use of hypervalent iodine-BF4 salt to fluorinate compounds.

Chem Comm paper