Antarlides

Masaya Imoto and co-workers from Keio University have reported in ACIE on some macrolides that acted as androgen receptor antagonists.

 

ACIE paper

Mandelalide A synthesis

Rich Carter and co-workers have reported in JACS on the synthesis of mandelalide.

 

 

JACS paper

Coibamide A synthesis

Wu Su and co-workers from the Chinese Academy of Sciences have reported in JACS on the synthesis of coibamide A.

JACS paper

Mycalolides synthesis

Hideo Kigoshi and co-workers from the University of Tsukuba have reported in ACIE on the synthesis of mycalolides.

ACIE paper

Nannocystin A

Dominic Hoepfner and co-workers from Novartis have reported in ACIE on nannocystin A, which had similar binding properties with didemin B on EF-1alpha (elongation factor 1 inhibitor).

ACIE paper

Mark Brönstrup and co-workers at Helmholtz Zentrum für Infektionsforschung also reported on the isolation of this small molecule. I wonder if there’s a relationship between the two studies.

ACIE paper

the novartis paper states that their study parallels the work in helmholtz. I guess the two studies just coincidentally resulted in the isolation of the same compound.

Nanocystin A

Here’re some macrocycles reported in ACIE.

ACIE paper

Diazonamide analogs through electrochemistry

Patrick Harran and co-workers have reported in ACIE on an electrochemical approach to access diazonamide analogs.

ACIE paper

Brefeldin A synthesis

Alois Furstner and colleague have reported in ACIE on the synthesis of brefeldin A.

ACIE paper

Miuraenamide sythesis

Uli Kazmeier and co-workers at Saarland University have reported in ACIE on the synthesis of miuraenamides.

ACIE paper

Rakicidin A synthesis

Yue Chen and co-workers from Nankai University have reported in JACS on the synthesis of rakicidin A, which has inhibitory activity towards cancer stem cells.

 

 

JACS paper