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Archive for the ‘Macrocycles’ Category

Brefeldin A synthesis

Posted by naturalproductman on February 22, 2015

Alois Furstner and colleague have reported in ACIE on the synthesis of brefeldin A.

brefeldin A

ACIE paper

Posted in Macrocycles, Total Synthesis | Leave a Comment »

Miuraenamide sythesis

Posted by naturalproductman on February 22, 2015

Uli Kazmeier and co-workers at Saarland University have reported in ACIE on the synthesis of miuraenamides.

miuraenamides

ACIE paper

Posted in Macrocycles, Total Synthesis | Leave a Comment »

Rakicidin A synthesis

Posted by naturalproductman on October 7, 2014

Yue Chen and co-workers from Nankai University have reported in JACS on the synthesis of rakicidin A, which has inhibitory activity towards cancer stem cells.

 

 

JACS paper

Posted in Macrocycles, Total Synthesis | Leave a Comment »

Belizentrin synthesis

Posted by naturalproductman on August 18, 2014

Hernandez Daranas and co-workrs from the University of La Laguna in Spain have reported in Organic Letters on the isolation of belizentrin.

belizentrin

OL paper

Posted in Macrocycles | Leave a Comment »

Sarcophytonolide synthesis

Posted by naturalproductman on February 20, 2013

Isao Kadota and co-workers from Okayama University have reported in Org Lett on a synthesis of sarcophytonolide.

diastereomers

OL paper

Posted in Macrocycles, Methodology | Leave a Comment »

Selective macrocyclization

Posted by naturalproductman on April 23, 2012

Christopher Boddy and co-workers at the University of Ottawa have reported in Organic Letters on the selective macrocyclization using DEBS TE.

enzyme

OL paper

Posted in Chemical Biology, Enzymatic, Macrocycles, Macrolides, Methodology | Leave a Comment »

Roseophilin synthesis

Posted by naturalproductman on March 29, 2012

Bernard Flynn and colleague at Monash University in Australia have reported in Organic Letters on a novel approach to roseophilin.
roseophilin

OL paper

Posted in Alkaloids, Macrocycles, Methodology | Leave a Comment »

Okilactomycin synthesis

Posted by naturalproductman on January 24, 2012

Thomas Hoye and colleague at the University of Minnesota have reported in Organic Letters on a racemic synthesis of okilactomycin from an intramolecular Diels-Alder.

okilactomycin

OL paper

Posted in Cascade Reactions, Cycloaddition, Diels-Alder, Lactones, Macrocycles, Methodology, Named Reactions, Pericyclic reactions | Leave a Comment »

Gymnodimine synthesis

Posted by naturalproductman on November 16, 2011

Daniel Romo and co-workers have reported in JACS on a synthesis of gymnodimine.
alkaloid
JACS paper

Posted in Alkaloids, Cascade Reactions, cross coupling, Macrocycles, Methodology | Leave a Comment »

Norcembrenolides syntheses

Posted by naturalproductman on October 6, 2011

Emanuel Theodorakis and co-workers have reported in Organic Letters on the syntheses of norcembrenolides B and C.

norcembrenolide

OL paper

Posted in Macrocycles, Methodology | Leave a Comment »

 
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