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Archive for the ‘Paterno-Buchi’ Category

Frondosin via Paterno Buchi

Posted by naturalproductman on February 29, 2012

Jonathan George and co-workers at the University of Adelaide have reported in Organic Letters on a Paterno Buchi reaction approach to access the 5 membered ring of frondosin.

Paterno Buchi

OL paper

Posted in Alkaloids, Cycloaddition, Light Mediated, Methodology, Named Reactions, Paterno-Buchi, Pericyclic reactions, [2+2] | Leave a Comment »

[2+2] Catalyzed by a Cytochrome P450

Posted by naturalproductman on October 14, 2010

Cytochrome P450 enzymes are usually notorious with their hydroxylation reactions, however F. Peter Guengerich and co-workers at Vanderbilt have shown that they can also catalyze [2+2] reactions to form an oxetane ring.


JACS paper

Posted in Chemical Biology, Enzymatic, Iron, Methodology, Named Reactions, Paterno-Buchi, Transition Metal | Leave a Comment »