Psiguadial B synthesis

Sarah Reisman and co-workers have reported in JACS on the synthesis of psiguadial B. The key step was a Wolff rearrangement using a Honeywell UV lamp. The supporting information has a nice picture of the reaction set up. It looks like you just shine the lamp next to the reaction flask with aluminum foil around it.

 

JACS paper

Ketene from a Diazo Compound

Gunda Georg and co-worker at the University of Minnesota have published in JACS on a silver promoted Wolff rearrangement to access dihydropiperidones via a 6-exo-dig cyclization.

JACS paper